Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | CDK9 | P50750 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10344697 | 0.81 | POLB (0.68) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL8746726 | 0.80 | MEN1 (1.00) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL4831443 | 0.80 | BCHE (0.46) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL26229535 | 0.78 | TAAR1 (0.62) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL305498 | 0.77 | TAAR1 (1.00) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL8946928 | 0.77 | TAAR1 (0.60) | HTTIMPDH2TAAR1SMN1; SMN2TP53 | |
| SCHEMBL23319507 | 0.76 | ALDH1A1 (0.54) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL10665495 | 0.76 | RAB9A (0.79) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL2892111 | 0.76 | HTT (0.56) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL16305298 | 0.75 | CA1 (0.46) | NPC1RAB9AMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31550-E | N-(2-Chloro-4-pyridyl) ureas | Shudo, Koichi (JP) | 1984-04-10 | — | — | US | disclosed |
| US-4193788-A | N-(2-Chloro-4-pyridyl)ureas | ISOGAI YO (JP) | 1980-03-18 | — | — | US | disclosed |