Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | F9 | P00740 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4425566 | 0.83 | KMO (0.67) | NOTUMSLC6A3SLC6A2KMOKDM4E | |
| SCHEMBL5937430 | 0.83 | EGLN1 (0.57) | MAPK1SLC6A3SLC6A2KDM4EPKM | |
| SCHEMBL4780370 | 0.81 | KMO (0.68) | KMOKDM4E | |
| SCHEMBL27772735 | 0.79 | MAPK1 (0.53) | NOTUMMAPK1SLC6A3KDM4EDYRK1A | |
| SCHEMBL11047919 | 0.79 | MAPK1 (0.59) | MAPK1DYRK1APDGFRBPDGFRA | |
| SCHEMBL13680499 | 0.78 | MAPK1 (0.51) | MAPK1KMOKDM4EDYRK1A | |
| SCHEMBL2037294 | 0.78 | MAPK1 (0.59) | MAPK1KDM4EDYRK1APDGFRBPDGFRA | |
| SCHEMBL11041168 | 0.78 | MAPK1 (0.59) | MAPK1KDM4EDYRK1A | |
| SCHEMBL8258906 | 0.77 | MAPK1 (0.54) | MAPK1KDM4EPKMDYRK1A | |
| SCHEMBL23380565 | 0.77 | MAPT (0.51) | MAPK1KDM4EDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1984004302-A1 | SUBSTITUTED PICOLINIC ACIDS, PROCESSES FOR THEIR PREPARATION, THEIR USE AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1984-11-08 | — | — | WO | disclosed |