Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL52642 | 1.00 | HTR2A (0.53) | HTR2ASLC6A2SLC6A4HTR2CDRD2 | |
| SCHEMBL195468 | 1.00 | HTR2A (0.53) | HTR2ASLC6A2SLC6A4HTR2CDRD2 | |
| SCHEMBL11049835 | 0.99 | HTR2A (0.51) | HTR2ASLC6A2SLC6A4HTR2CDRD2 | |
| SCHEMBL10791951 | 0.94 | HTR2A (0.48) | HTR2ASLC6A2SLC6A4HTR2CDRD2 | |
| SCHEMBL4379538 | 0.89 | HTR2A (0.39) | HTR2ASLC6A2SLC6A4HTR2CDRD2 | |
| SCHEMBL166962 | 0.83 | CYP1A2 (0.38) | HTR2ASLC6A2SLC6A4HTR2CDRD2 | |
| SCHEMBL2307403 | 0.80 | TDP1 (0.36) | HTR2ASLC6A2SLC6A4HTR2CDRD2 | |
| SCHEMBL18123684 | 0.77 | IDO1 (0.32) | ALDH1A1TP53 | |
| SCHEMBL333858 | 0.76 | GABRA1 (0.35) | HTR2AHTR2CALDH1A1 | |
| SCHEMBL9597806 | 0.76 | HTR2A (0.59) | HTR2ASLC6A2SLC6A4HTR2CDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036075-B1 | MIXTURES BASED ON AROMATIC-ALIPHATIC KETONES, THEIR USE AS PHOTOINITIATORS AND PHOTOPOLYMERISABLE SYSTEMS CONTAINING SUCH MIXTURES | MERCK PATENT GmbH (DE) | 1984-06-06 | — | — | EP | disclosed |
| US-4434035-A | Mixtures of aromatic-aliphatic ketones as photoinitiators and photopolymerizable systems containing them | Merck Patent Gesellschaft mit beschr/a/ nkter Haftung (DE) | 1984-02-28 | — | — | US | disclosed |
| US-4390453-A | DISCOLORATION INHIBITION; ULTRAVIOLET HARDENING OF ACRYLIC INKS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-06-28 | — | — | US | disclosed |
| EP-0036075-A1 | Mixtures based on aromatic-aliphatic ketones, their use as photoinitiators and photopolymerisable systems containing such mixtures | MERCK PATENT GmbH (DE) | 1981-09-23 | — | — | EP | disclosed |