SCHEMBL11050433

SCHEMBL11050433

O=C(CBr)OC/C(I)=C(/Br)I

nearest known ligand 0.44

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP2C19 P33261 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11050446 1.00 TRPA1 (0.44) TRPA1ALDH1A1CYP2C19L3MBTL1
SCHEMBL11051111 0.84 TRPA1 (0.46) TRPA1ALDH1A1CYP2C19L3MBTL1
SCHEMBL11057617 0.80
SCHEMBL8501977 0.80 NAAA (0.38) TRPA1ALDH1A1CYP2C19
SCHEMBL11057616 0.80
SCHEMBL11056307 0.80 NAAA (0.38) TRPA1ALDH1A1CYP2C19
SCHEMBL11056938 0.77
SCHEMBL11058254 0.77 ALDH1A1 (0.43) TRPA1ALDH1A1L3MBTL1
SCHEMBL11058250 0.77 ALDH1A1 (0.43) TRPA1ALDH1A1L3MBTL1
SCHEMBL11056936 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4487781-A HEAT RESISTANCE; PHOTOSTABILITY SANKYO COMPANY LIMITED (JP) 1984-12-11 US disclosed