Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | CASP3 | P42574 | 2/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | AHR | P35869 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29644384 | 0.80 | NPC1 (1.00) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL2048865 | 0.80 | NPC1 (1.00) | RAB9AMAPTNPC1MEN1KMT2A | |
| SCHEMBL15945345 | 0.77 | MAPT (0.55) | RAB9ASMN1; SMN2MAPTNPC1MEN1 | |
| SCHEMBL25256045 | 0.77 | RAB9A (0.51) | RAB9ASMN1; SMN2MAPTNPC1MEN1 | |
| SCHEMBL29508633 | 0.77 | RAB9A (0.51) | RAB9ASMN1; SMN2MAPTNPC1MEN1 | |
| SCHEMBL30201832 | 0.76 | SMN1; SMN2 (0.60) | RAB9ASMN1; SMN2MAPTNPC1MEN1 | |
| Methyl Alcohol SCHEMBL11080000 | 0.76 | NPC1 (0.66) | RAB9ASMN1; SMN2MAPTNPC1MEN1 | |
| SCHEMBL11083265 | 0.76 | ADORA3 (0.63) | RAB9ASMN1; SMN2MAPTNPC1MEN1 | |
| SCHEMBL1352961 | 0.75 | KDM4E (0.51) | RAB9ASMN1; SMN2MAPTNPC1MEN1 | |
| SCHEMBL10062017 | 0.75 | NPC1 (1.00) | RAB9ASMN1; SMN2NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0070767-B1 | QUINOLINE DERIVATIVES, THEIR SALTS, THEIR PREPARATION, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1985-04-10 | — | — | EP | disclosed |