Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 6/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.34 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 4/20 | 0.33 |
| ▸ | REN | P00797 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013364 | 0.73 | ALDH1A1 (0.37) | ADRA2APDE4AADRA1AALDH1A1SMN1; SMN2 | |
| SCHEMBL3396586 | 0.73 | DPP4 (0.49) | ALDH1A1DPP4HTR1AHTR7ACE | |
| SCHEMBL19347391 | 0.73 | PIK3CA (0.40) | PMP22MEN1KMT2ADPP4ACE | |
| SCHEMBL670375 | 0.73 | DPP4 (0.49) | ALDH1A1DPP4HTR1AHTR7ACE | |
| SCHEMBL1239264 | 0.73 | DPP4 (0.49) | ALDH1A1DPP4HTR1AHTR7ACE | |
| SCHEMBL3817074 | 0.69 | HTT (0.45) | HTTDPP4SPHK2SPHK1ACE | |
| SCHEMBL30305372 | 0.69 | HTT (0.45) | HTTDPP4SPHK2SPHK1ACE | |
| SCHEMBL8591233 | 0.69 | HTT (0.45) | HTTDPP4SPHK2SPHK1ACE | |
| Hydrochloric Acid SCHEMBL9837699 | 0.69 | DPP4 (0.40) | DPP4HTR1AHTR7SPHK2SPHK1 | |
| SCHEMBL22481429 | 0.68 | DPP4 (0.45) | DPP4HTR1AHTR7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452814-A | ANTITUMOR AGENTS | SUAMI T (JP) | 1984-06-05 | — | — | US | disclosed |