Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL893369 | 0.80 | ALDH1A1 (0.59) | ALDH1A1POLBKMT2ATLR8CYP1A2 | |
| SCHEMBL10352847 | 0.76 | TLR8 (0.61) | ALDH1A1POLBKMT2ATLR8CYP1A2 | |
| SCHEMBL1829325 | 0.74 | ALDH1A1 (0.53) | ALDH1A1POLBKMT2ATLR8CYP1A2 | |
| SCHEMBL2960713 | 0.74 | ALDH1A1 (0.53) | ALDH1A1POLBKMT2ATLR8CYP1A2 | |
| SCHEMBL28837797 | 0.73 | TLR8 (0.57) | ALDH1A1POLBKMT2ATLR8LMNA | |
| SCHEMBL4918147 | 0.73 | CHRNB2 (0.41) | KMT2AHTTKDM4E | |
| SCHEMBL329177 | 0.73 | ALDH1A1 (1.00) | ALDH1A1POLBKMT2ATLR8CYP1A2 | |
| SCHEMBL28276561 | 0.73 | ALDH1A1 (1.00) | ALDH1A1POLBKMT2ATLR8CYP1A2 | |
| SCHEMBL3171422 | 0.73 | ALDH1A1 (0.51) | ALDH1A1POLBKMT2ATLR8CYP1A2 | |
| SCHEMBL6115119 | 0.72 | ALDH1A1 (0.69) | ALDH1A1POLBKMT2ATLR8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000951-B1 | PHARMACEUTICAL FORMULATIONS COMPRISING 1-SUBSTITUTED IMIDAZOLES, 1-SUBSTITUTED IMIDAZOLES AND 1-SUBSTITUTED IMIDAZOLES FOR USE IN THE TREATMENT OR PROPHYLAXIS OF THROMBO-EMBOLIC DISORDERS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-05-23 | — | — | EP | disclosed |
| US-4284641-A | ANTITHROMBOEMBOLIC AGENT | BURROUGHS WELLCOME CO. (US) | 1981-08-18 | — | — | US | disclosed |
| EP-0000951-A1 | Pharmaceutical Formulations comprising 1-substituted imidazoles, 1-substituted imidazoles and 1-substituted imidazoles for use in the treatment or prophylaxis of thrombo-embolic disorders | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-03-07 | — | — | EP | disclosed |