Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ATP4A | P20648 | 1/20 | 0.35 |
| ▸ | ATP4B | P51164 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11051880 | 0.87 | ALDH1A1 (0.47) | HCAR1ALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL21621663 | 0.86 | ALDH1A1 (0.41) | HCAR1ALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL11047604 | 0.82 | HCAR1 (0.45) | HCAR1ALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL11101297 | 0.73 | FGFR1 (0.47) | ALDH1A1HPGDHSD17B10CYP1A2CYP2D6 | |
| SCHEMBL29051025 | 0.73 | PI4KA (0.42) | HCAR1ALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL2238527 | 0.71 | NOTUM (0.38) | HCAR1ALDH1A1HPGDHSD17B10CYP1A2 | |
| SCHEMBL9518250 | 0.70 | ALDH1A1 (0.34) | ALDH1A1HPGDHSD17B10CYP1A2CYP2D6 | |
| SCHEMBL11048752 | 0.69 | CPB1 (0.43) | HCAR1ALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL23458074 | 0.67 | CCR1 (0.34) | ALDH1A1KMT2ATDP1MAPTSMN1; SMN2 | |
| SCHEMBL23458100 | 0.67 | ALDH1A1 (0.43) | ALDH1A1HPGDHSD17B10CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443466-A | DIURETICS, SEDATIVES, ANALGESICS | Farmos-Yhtyma OY (Farmos Group Ltd.) (FI) | 1984-04-17 | — | — | US | claimed |
| EP-0024829-B1 | 4-BENZYL- AND 4-BENZOYLIMIDAZOLE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Farmos-Yhtyma Oy (FI) | 1984-04-25 | — | — | EP | disclosed |
| US-4443466-A | DIURETICS, SEDATIVES, ANALGESICS | Farmos-Yhtyma OY (Farmos Group Ltd.) (FI) | 1984-04-17 | — | — | US | disclosed |