Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 4/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.56 |
| ▸ | PPARG | P37231 | 4/20 | 0.56 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | MMP3 | P08254 | 2/20 | 0.52 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8845789 | 1.00 | PTGES (0.56) | PTGESALOX5PPARGGRIK1MMP2 | |
| SCHEMBL355603 | 0.97 | GRIK1 (0.55) | PTGESALOX5PPARGGRIK1CPB2 | |
| SCHEMBL30839920 | 0.97 | GRIK1 (0.55) | PTGESALOX5PPARGGRIK1CPB2 | |
| SCHEMBL10869949 | 0.97 | GRIK1 (0.55) | PTGESALOX5PPARGGRIK1CPB2 | |
| SCHEMBL5385323 | 0.97 | GRIK1 (0.55) | PTGESALOX5PPARGGRIK1CPB2 | |
| SCHEMBL11305180 | 0.97 | GRIK1 (0.55) | PTGESALOX5PPARGGRIK1CPB2 | |
| SCHEMBL28807882 | 0.94 | GRIK1 (0.59) | PTGESALOX5PPARGGRIK1MMP2 | |
| SCHEMBL8904462 | 0.94 | GRIK1 (0.59) | PTGESALOX5PPARGGRIK1MMP2 | |
| SCHEMBL1131425 | 0.93 | GRIK1 (0.62) | PTGESALOX5PPARGGRIK1MMP2 | |
| SCHEMBL8904064 | 0.92 | GRIK1 (0.60) | PTGESALOX5PPARGGRIK1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790824-A1 | 2,2-DICHLOROALKANE CARBOXYLIC ACIDS, PROCESS FOR PREPARING THE SAME, MEDICAMENT CONTAINING THE SAME, AND USE THEREOF FOR TREATING INSULIN RESISTANCE | Roche Diagnostics GmbH (DE) | 1997-08-27 | — | — | EP | disclosed |
| WO-1996015784-A2 | 2,2-DICHLOROALKANE CARBOXYLIC ACIDS, PROCESS FOR PREPARING THE SAME, MEDICAMENT CONTAINING THE SAME, AND USE THEREOF FOR TREATING INSULIN RESISTANCE | BOEHRINGER MANNHEIM GMBH (DE) | 1996-05-30 | — | — | WO | disclosed |