Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | VEGFA | P15692 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7888451 | 0.85 | GRIN2D (0.40) | KDM4EAPEX1L3MBTL1FABP4ALDH1A1 | |
| SCHEMBL11339850 | 0.84 | KDM4E (0.42) | KDM4EL3MBTL1HSD17B10MAPTALDH1A1 | |
| SCHEMBL7891026 | 0.84 | MEN1 (0.42) | KDM4EL3MBTL1HSD17B10MAPTALDH1A1 | |
| SCHEMBL11053467 | 0.82 | ALDH1A1 (0.33) | KDM4EL3MBTL1MAPTALDH1A1NPSR1 | |
| SCHEMBL11290276 | 0.81 | ALDH1A1 (0.49) | KDM4EL3MBTL1POLBMAPTALDH1A1 | |
| SCHEMBL6875333 | 0.80 | KDM4E (0.40) | KDM4EL3MBTL1POLBMAPTALDH1A1 | |
| SCHEMBL11334497 | 0.80 | ALDH1A1 (0.45) | KDM4EPOLBHSD17B10MAPTALDH1A1 | |
| SCHEMBL7888404 | 0.80 | KDM4E (0.41) | KDM4EL3MBTL1HSD17B10MAPTALDH1A1 | |
| SCHEMBL7890128 | 0.77 | KDM4E (0.51) | KDM4EL3MBTL1POLBHSD17B10MAPT | |
| SCHEMBL7883059 | 0.75 | KDM4E (0.42) | KDM4EAPEX1L3MBTL1POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0078024-B1 | WATER-SOLUBLE PYRIDONE AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-19 | — | — | EP | disclosed |