SCHEMBL7888451

SCHEMBL7888451

Cc1cc(O)n(CC(=O)O)c(=O)c1S(=O)(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIA1 P42261 1/20 0.40
GRIA2 P42262 1/20 0.40
GRIA3 P42263 1/20 0.40
GRIA4 P48058 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
GRIN3A Q8TCU5 1/20 0.40
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 5/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
MCOLN3 Q8TDD5 1/20 0.35
LMNA P02545 2/20 0.35
FABP4 P15090 1/20 0.35
MAPK1 P28482 1/20 0.35
STAT3 P40763 1/20 0.35
CNR1 P21554 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11051169 0.85 KDM4E (0.41) KDM4EALDH1A1L3MBTL1FABP4APEX1
SCHEMBL6875333 0.83 KDM4E (0.40) KDM4EALDH1A1L3MBTL1MCOLN3LMNA
SCHEMBL7891026 0.80 MEN1 (0.42) KDM4EALDH1A1L3MBTL1MCOLN3LMNA
SCHEMBL11339850 0.80 KDM4E (0.42) KDM4EALDH1A1L3MBTL1MCOLN3LMNA
SCHEMBL11053467 0.79 ALDH1A1 (0.33) KDM4EALDH1A1L3MBTL1MCOLN3LMNA
SCHEMBL11290276 0.78 ALDH1A1 (0.49) KDM4EALDH1A1L3MBTL1MCOLN3LMNA
SCHEMBL11334497 0.77 ALDH1A1 (0.45) KDM4EALDH1A1MAPK1MEN1KMT2A
SCHEMBL7888404 0.76 KDM4E (0.41) KDM4EALDH1A1L3MBTL1MCOLN3LMNA
SCHEMBL1165297 0.75 LMNA (0.55) KDM4EALDH1A1LMNAMAPK1STAT3
SCHEMBL7893145 0.74 ALDH1A1 (0.34) KDM4EALDH1A1L3MBTL1MCOLN3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6177552-B1 CONTAINING (((VINYLSULFONYL)ALKYLAMINO)ALKYLSULFONYL)PHENYLAZO GROUPS DYSTARTEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2001-01-23 US disclosed
EP-0489360-B1 Water-soluble azocompounds, process for their preparation and their use as dyes HOECHST AG (DE) 1995-09-20 EP disclosed
EP-0399411-B1 Water soluble azo compounds, process for their preparation and their use as dyestuffs HOECHST AG (DE) 1994-07-13 EP disclosed
EP-0381133-B1 Water soluble azo compounds, method for their preparation and their use as dyestuffs HOECHST AG (DE) 1994-03-02 EP disclosed
EP-0384276-B1 Water soluble azo compounds, method for their preparation and their use as dyestuffs HOECHST AG (DE) 1993-11-10 EP disclosed
US-5216138-A With vinyl sulfonyl group HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-01 US disclosed
EP-0489360-A1 Water-soluble azocompounds, process for their preparation and their use as dyes HOECHST AKTIENGESELLSCHAFT (DE) 1992-06-10 EP disclosed
US-5021559-A Water-soluble azo compounds containing a fiber-reactive group of the vinylsulfone series, suitable as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1991-06-04 US disclosed
US-5010180-A Printing, dyeing HOECHST AKTIENGESELLSCHAFT (DE) 1991-04-23 US disclosed
EP-0399411-A1 Water soluble azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-28 EP disclosed
EP-0384276-A1 Water soluble azo compounds, method for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-29 EP disclosed
EP-0381133-A1 Water soluble azo compounds, method for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-08 EP disclosed
EP-0181585-A2 Fibre-reactive monoazo compounds, process for their preparation and their dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1986-05-21 EP disclosed
EP-0078009-B1 WATER-SOLUBLE PYRIDONE AZO COMPOUNDS; PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1985-08-07 EP disclosed
EP-0078009-A1 Water-soluble pyridone azo compounds; process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1983-05-04 EP disclosed
EP-0078024-A1 Water-soluble pyridone azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1983-05-04 EP disclosed