Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11055845 | 0.93 | OPRM1 (0.53) | HTR1AOPRM1OPRK1HDAC8HDAC1 | |
| SCHEMBL9387259 | 0.88 | OPRM1 (0.48) | HTR1AOPRM1OPRK1HDAC8HDAC1 | |
| SCHEMBL9387516 | 0.81 | OPRM1 (0.57) | OPRM1OPRK1HDAC8HDAC1HDAC2 | |
| SCHEMBL10642465 | 0.72 | OPRM1 (0.50) | HTR1AOPRM1OPRK1HDAC8HDAC1 | |
| Hydrochloric Acid SCHEMBL10640540 | 0.71 | OPRM1 (0.49) | HTR1AOPRM1OPRK1HDAC8HDAC1 | |
| SCHEMBL10686767 | 0.68 | OPRM1 (0.49) | HTR1AOPRM1OPRK1HDAC8HDAC1 | |
| SCHEMBL9599601 | 0.68 | OPRM1 (0.51) | OPRM1OPRK1HDAC8HDAC1HDAC2 | |
| SCHEMBL5527596 | 0.68 | OPRM1 (0.48) | OPRM1OPRK1HDAC8HDAC1HDAC2 | |
| SCHEMBL27901582 | 0.68 | OPRM1 (0.56) | OPRM1OPRK1HDAC8HDAC1HDAC2 | |
| SCHEMBL15100399 | 0.67 | PRCP (0.56) | OPRM1OPRK1HDAC8HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4466967-A | NONTOXIC INSECTICIDES | ROHM AND HAAS COMPANY (US) | 1984-08-21 | — | — | US | disclosed |
| US-4419360-A | UREA OR THIOUREA DERIVATIVES | ROHM AND HAAS COMPANY (US) | 1983-12-06 | — | — | US | disclosed |