Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 4/20 | 0.87 |
| ▸ | TUBB | P07437 | 4/20 | 0.87 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.87 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.87 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.87 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.87 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.87 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.87 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.87 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.87 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.87 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.87 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.87 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.87 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.87 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.83 |
| ▸ | TSHR | P16473 | 1/20 | 0.83 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.83 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.83 |
| ▸ | P4HB | P07237 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15444095 | 1.00 | TUBB4A (0.87) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27094854 | 1.00 | TUBB4A (0.87) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL20382874 | 1.00 | TUBB4A (0.87) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL25641500 | 1.00 | TUBB4A (0.87) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL18123864 | 1.00 | TUBB4A (0.87) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL23542054 | 1.00 | TUBB4A (0.87) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL13312348 | 1.00 | TUBB4A (0.87) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL17516495 | 1.00 | TUBB4A (0.87) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16103877 | 0.96 | TUBB4A (0.88) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL22503914 | 0.96 | TUBB4A (0.88) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230181755-A1 | ANTITUMOR COMBINATIONS CONTAINING ANTI-CEACAM5 ANTIBODY CONJUGATES, TRIFLURIDINE AND TIPIRACIL | SANOFI (FR) | 2023-06-15 | — | — | US | disclosed |
| US-8987424-B2 | CA6 antigen-specific cytotoxic conjugate and methods of using the same | IMMUNOGEN, INC. (US) | 2015-03-24 | — | — | US | disclosed |
| WO-2014134483-A2 | CONJUGATES COMPRISING CELL-BINDING AGENTS AND CYTOTOXIC AGENTS | IMMUNOGEN, INC. (US) | 2014-09-04 | — | — | WO | disclosed |
| US-8153765-B2 | Anti-CD38 antibodies for the treatment of cancer | Sanof Aventis (FR) | 2012-04-10 | — | — | US | disclosed |
| US-20090099336-A1 | using the conjugates in the inhibition of cell growth; cancer; monoclonal antibody or epitope-binding fragment thereof, that recognizes and binds the CA6 glycotope | IMMUNOGEN INC. | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090099336-A1 | using the conjugates in the inhibition of cell growth; cancer; monoclonal antibody or epitope-binding fragment thereof, that recognizes and binds the CA6 glycotope | CA6, CA14, CA13 | TUBB4A 3340/4885TUBB 4079/4885TUBA3C 2911/4885 |
| US-20230181755-A1 | ANTITUMOR COMBINATIONS CONTAINING ANTI-CEACAM5 ANTIBODY CONJUGATES, TRIFLURIDINE AND TIPIRACIL | TAS2R5, TMEM205, CD99 | TUBB4A 853/4885TUBB 690/4885TUBA3C 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.