Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL11051491

CC(C)(N)C(=O)N[C@H](CCC(=O)OCc1ccccc1)C(N)=O.O=C(O)C(F)(F)F

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSL P07711 2/20 0.45
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.45
KMT2A Q03164 1/20 0.45
SIRT2 Q8IXJ6 1/20 0.43
PTPN1 P18031 3/20 0.43
REN P00797 2/20 0.42
GHSR Q92847 1/20 0.40
BCHE P06276 2/20 0.40
ACHE P22303 2/20 0.40
F10 P00742 1/20 0.40
PRSS1 P07477 1/20 0.40
CACNA1F O60840 1/20 0.40
CACNA1D Q01668 1/20 0.40
CACNA1S Q13698 1/20 0.40
CACNA1C Q13936 1/20 0.40
PADI1 Q9ULC6 1/20 0.39
PADI4 Q9UM07 1/20 0.39
PADI2 Q9Y2J8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL11566608 1.00 CTSL (0.45) CTSLMEN1ALDH1A1HPGDKMT2A
SCHEMBL11050892 0.94 ALDH1A1 (0.48) CTSLMEN1ALDH1A1HPGDKMT2A
Trifluoroacetic Acid SCHEMBL11275189 0.85 CTSL (0.53) CTSLMEN1ALDH1A1HPGDKMT2A
Trifluoroacetic Acid SCHEMBL25383492 0.85 CTSL (0.53) CTSLMEN1ALDH1A1HPGDKMT2A
Trifluoroacetic Acid SCHEMBL966704 0.83 CTSL (0.51) CTSLMEN1ALDH1A1HPGDKMT2A
SCHEMBL10887447 0.82 PPARA (0.53) CTSLMEN1ALDH1A1HPGDKMT2A
SCHEMBL14997847 0.82 PPARA (0.53) CTSLMEN1ALDH1A1HPGDKMT2A
SCHEMBL11599337 0.82 PPARA (0.53) CTSLMEN1ALDH1A1HPGDKMT2A
SCHEMBL4910504 0.81 CTSL (0.60) CTSLMEN1ALDH1A1HPGDKMT2A
SCHEMBL4910499 0.81 CTSL (0.60) CTSLMEN1ALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4430265-A IMMUNOSTIMULATORY ACTIVITY TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1984-02-07 US disclosed
EP-0002677-B1 GLUCOSAMINE-PEPTIDE DERIVATIVES AND THEIR PHARMACEUTICAL COMPOSITIONS Takeda Chemical Industries, Ltd. (JP) 1982-10-13 EP disclosed