Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL11275189

C[C@H](N)C(=O)N[C@H](CCC(=O)OCc1ccccc1)C(N)=O.O=C(O)C(F)(F)F

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CTSL P07711 2/20 0.53
PTPN1 P18031 6/20 0.48
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
KMT2A Q03164 1/20 0.47
CTRB1 P17538 3/20 0.45
SIRT2 Q8IXJ6 1/20 0.43
CTSS P25774 1/20 0.43
CTSK P43235 1/20 0.42
REN P00797 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL25383492 1.00 CTSL (0.53) CTSLPTPN1MEN1ALDH1A1HPGD
SCHEMBL9437417 0.93 CTSL (0.53) CTSLPTPN1MEN1ALDH1A1HPGD
SCHEMBL20583780 0.93 CTSL (0.53) CTSLPTPN1MEN1ALDH1A1HPGD
Hydrochloric Acid SCHEMBL7779525 0.92 CTSL (0.52) CTSLPTPN1MEN1ALDH1A1HPGD
Hydrochloric Acid SCHEMBL11290000 0.92 CTSL (0.52) CTSLPTPN1MEN1ALDH1A1HPGD
Trifluoroacetic Acid SCHEMBL966704 0.90 CTSL (0.51) CTSLPTPN1MEN1ALDH1A1HPGD
Trifluoroacetic Acid SCHEMBL31360487 0.85 CTSL (0.45) CTSLPTPN1MEN1ALDH1A1HPGD
Trifluoroacetic Acid SCHEMBL31360749 0.85 CTSL (0.45) CTSLPTPN1MEN1ALDH1A1HPGD
SCHEMBL8851538 0.85 ALDH1A1 (0.53) CTSLMEN1ALDH1A1HPGDKMT2A
SCHEMBL8851532 0.85 ALDH1A1 (0.53) CTSLMEN1ALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250170237-A1 MURAMYL DIPEPTIDES AND PROCESS FOR PREPARATION THEREOF UNIVERSITEIT GENT (BE) 2025-05-29 US claimed
EP-4482849-A1 MURAMYL DIPEPTIDES AND PROCESS FOR PREPARATION THEREOF Council of Scientific & Industrial Research (IN) 2025-01-01 EP claimed
WO-2023161962-A1 MURAMYL DIPEPTIDES AND PROCESS FOR PREPARATION THEREOF COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2023-08-31 WO claimed
EP-3389643-B1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF BHARAT BIOTECH INT LTD (IN) 2023-05-03 EP claimed
CN-108884132-B Muramyl peptide derivatives a compound their synthesis and their use 巴拉特生物技术国际有限公司 2022-10-04 CN claimed
EP-3387005-B1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF BHARAT BIOTECH INT LTD (IN) 2022-08-24 EP claimed
CN-108883080-B Muramyl peptide derivative compounds, their synthesis and use thereof 巴拉特生物技术国际有限公司 2021-12-21 CN claimed
US-10576147-B2 Muramyl peptide derivative compound, synthesis and uses thereof BHARAT BIOTECH INTERNATIONAL LIMITED (IN) 2020-03-03 US claimed
US-20180371023-A1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF BHARAT BIOTECH INTERNATIONAL LIMITED (IN) 2018-12-27 US claimed
US-20180360957-A1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF BHARAT BIOTECH INTERNATIONAL LIMITED (IN) 2018-12-20 US claimed
EP-3389643-A1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF Bharat Biotech International Limited (IN) 2018-10-24 EP claimed
EP-3387005-A1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF Bharat Biotech International Limited (IN) 2018-10-17 EP claimed
WO-2017103944-A1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF BHARAT BIOTECH INTERNATIONAL LIMITED (IN) 2017-06-22 WO claimed
WO-2017098529-A1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF BHARAT BIOTECH INTERNATIONAL LIMITED (IN) 2017-06-15 WO claimed
US-20250170237-A1 MURAMYL DIPEPTIDES AND PROCESS FOR PREPARATION THEREOF UNIVERSITEIT GENT (BE) 2025-05-29 US disclosed
WO-2025027624-A1 CYCLIC GLYCOLIPOPEPTIDE VACCINE ADJUVANTS AND THE PROCESS FOR PREPARATION THEREOF COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) 2025-02-06 WO disclosed
EP-4482849-A1 MURAMYL DIPEPTIDES AND PROCESS FOR PREPARATION THEREOF Council of Scientific & Industrial Research (IN) 2025-01-01 EP disclosed
EP-0015468-B1 6-DEOXYGLUCOSAMINE-PEPTIDE DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1982-12-29 EP disclosed
US-4314998-A 6-Deoxyglucosamine-peptide derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1982-02-09 US disclosed
EP-0015468-A1 6-Deoxyglucosamine-peptide derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1980-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180360957-A1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF NOD2, HM13, HLA-DRB1 CTSL 1279/4885PTPN1 4054/4885MEN1 1033/4885
US-10576147-B2 Muramyl peptide derivative compound, synthesis and uses thereof NOD2, HM13, QRFPR CTSL 1317/4885PTPN1 4177/4885MEN1 854/4885
US-20250170237-A1 MURAMYL DIPEPTIDES AND PROCESS FOR PREPARATION THEREOF NOD2, NOD1, TLR9 CTSL 1704/4885PTPN1 2195/4885MEN1 1601/4885
US-20180371023-A1 NOVEL MURAMYL PEPTIDE DERIVATIVE COMPOUND, SYNTHESIS AND USES THEREOF NOD2, MICA, TLR9 CTSL 1056/4885PTPN1 3277/4885MEN1 1484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.