Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11056340 | 0.91 | KMT2A (0.53) | TSHRGAAKMT2ALMNASMN1; SMN2 | |
| SCHEMBL10979812 | 0.85 | GAA (0.46) | TSHRCHRM3GAAKMT2ALMNA | |
| SCHEMBL11054892 | 0.81 | KMT2A (0.51) | GAAKMT2ALMNAMEN1HTT | |
| SCHEMBL10928910 | 0.80 | TSHR (0.50) | TSHRCHRM3HTTALDH1A1HSD17B10 | |
| SCHEMBL10832448 | 0.80 | KMT2A (0.53) | GAAKMT2ALMNAMEN1HTT | |
| SCHEMBL10832100 | 0.80 | ALDH1A1 (0.50) | KMT2ALMNAMEN1HTTMAPT | |
| SCHEMBL1559433 | 0.77 | GAA (0.74) | TSHRCHRM3GAAKMT2ALMNA | |
| SCHEMBL10981870 | 0.77 | GAA (0.47) | GAAKMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL10983498 | 0.76 | GAA (0.47) | GAAKMT2ALMNASMN1; SMN2MEN1 | |
| SCHEMBL10958599 | 0.75 | PTGS2 (0.43) | TSHRKMT2ALMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4453001-A | ANTIDIABETIC AGENTS | SANDOZ, INC. (US) | 1984-06-05 | — | — | US | disclosed |
| US-4415568-A | ANTIDIABETIC AND HYPOGLYCEMIC AGENTS | SANDOZ, INC. (US) | 1983-11-15 | — | — | US | disclosed |
| US-4336378-A | ANTIDIABETIC AGENTS | SANDOZ, INC. (US) | 1982-06-22 | — | — | US | disclosed |