Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.54 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11049406 | 0.89 | MAPT (0.55) | ALDH1A1CYP3A4CA2LMNAMAPK1 | |
| SCHEMBL19253806 | 0.87 | ALDH1A1 (0.52) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL19024892 | 0.81 | ALDH1A1 (0.63) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL11177661 | 0.81 | ALDH1A1 (0.63) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| Biphenyl SCHEMBL28032501 | 0.80 | ALDH1A1 (0.67) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL21599117 | 0.80 | LMNA (0.47) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL10756303 | 0.80 | MAPT (0.55) | ALDH1A1LMNAMAPK1TSHRTDP1 | |
| SCHEMBL16672556 | 0.80 | L3MBTL1 (0.57) | ALDH1A1CYP3A4LMNAMAPK1TSHR | |
| SCHEMBL28023159 | 0.80 | ALDH1A1 (0.62) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL13228171 | 0.78 | LMNA (0.47) | ALDH1A1CYP3A4CA2LMNAPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464290-A | REMOVAL OF CONIFERYL BENZOATE AND ACETATE | SHISEIDO COMPANY LTD. (JP) | 1984-08-07 | — | — | US | disclosed |