Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 3/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 2/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.38 |
| ▸ | TIMP3 | P35625 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11047493 | 0.93 | CASP6 (0.49) | CASP6CTDSP1ENPP2NT5EPRMT1 | |
| SCHEMBL11049670 | 0.93 | CASP6 (0.56) | CASP6CTDSP1ENPP2CA2CA3 | |
| SCHEMBL11074599 | 0.90 | CASP6 (0.60) | CASP6CTDSP1ENPP2CA2NT5E | |
| SCHEMBL11049548 | 0.87 | CASP6 (0.54) | CASP6CTDSP1ENPP2CA2NT5E | |
| SCHEMBL11067043 | 0.87 | APEX1 (0.48) | CASP6CTDSP1ENPP2NT5EPRMT1 | |
| SCHEMBL11049888 | 0.85 | ENPP2 (0.52) | CASP6CTDSP1ENPP2CA2NT5E | |
| SCHEMBL11050204 | 0.85 | NT5E (0.44) | CASP6CTDSP1ENPP2NT5EPRMT1 | |
| SCHEMBL11054880 | 0.84 | ENPP2 (0.50) | CASP6CTDSP1ENPP2CA2CA3 | |
| SCHEMBL11046439 | 0.84 | CASP6 (0.55) | CASP6CTDSP1ENPP2CA2NT5E | |
| SCHEMBL11051559 | 0.83 | ENPP2 (0.52) | CASP6CTDSP1ENPP2NT5EPRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473498-A | Water-soluble, fiber-reactive organic dyestuffs containing a β-chloro-ethylsulfonyl-methyl-benzoic acid amide group | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | disclosed |