Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13903991 | 0.84 | OPRM1 (0.42) | OPRM1OPRD1UHRF1KDM4EALDH1A1 | |
| SCHEMBL13953176 | 0.78 | KDM4E (0.50) | OPRM1OPRD1UHRF1KDM4EALDH1A1 | |
| SCHEMBL24335067 | 0.70 | AHR (0.48) | OPRM1OPRD1UHRF1KDM4EALDH1A1 | |
| SCHEMBL12328354 | 0.70 | KDM4E (0.53) | KDM4EALDH1A1HPGDGRIN2DGRIN3B | |
| SCHEMBL16127581 | 0.69 | KDM4E (0.60) | OPRM1OPRD1UHRF1KDM4EALDH1A1 | |
| SCHEMBL13560656 | 0.68 | GRIN2D (0.52) | KDM4EALDH1A1HPGDGRIN2DGRIN3B | |
| SCHEMBL29022540 | 0.68 | CHEK1 (0.56) | KDM4EALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL12219483 | 0.67 | KDM4E (0.46) | OPRM1OPRD1UHRF1KDM4EALDH1A1 | |
| SCHEMBL10045971 | 0.66 | GRIN2D (0.63) | KDM4EALDH1A1HPGDGRIN2DGRIN3B | |
| SCHEMBL15985685 | 0.65 | KIF11 (0.64) | KDM4EALDH1A1HPGDMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524116-B2 | Multilayer sheet containing optically anisotropic layer containing liquid crystal compound and cellulose ester with polymer | FUJIFILM CORPORATION (JP) | 2013-09-03 | — | — | US | disclosed |
| US-8164722-B2 | Liquid-crystal display device with at least three optically-anisotropic layers having formulated in-plane retardations | FUJIFILM CORPORATION (JP) | 2012-04-24 | — | — | US | disclosed |
| US-8153044-B2 | Heat treatment of thermoplastic film, and thermoplastic film and method for producing the same | FUJIFILM CORPORATION (JP) | 2012-04-10 | — | — | US | disclosed |
| US-8049849-B2 | Optical film, polarizing plate, and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2011-11-01 | — | — | US | disclosed |
| US-7951430-B2 | Cellulose acylate film, polarizing plate and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2011-05-31 | — | — | US | disclosed |
| US-7929087-B2 | Optical film, polarizing plate, and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2011-04-19 | — | — | US | disclosed |
| US-7872716-B2 | Optical compensation film, polarizing plate and liquid crystal display | FUJIFILM CORPORATION (JP) | 2011-01-18 | — | — | US | disclosed |
| US-7871538-B2 | Liquid crystal composition, retardation plate, and elliptic polarizing plate | FUJIFILM CORPORATION (JP) | 2011-01-18 | — | — | US | disclosed |
| US-7804565-B2 | Cellulose acylate film, optical compensation film, polarizing plate, and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2010-09-28 | — | — | US | disclosed |
| US-7799242-B2 | Liquid crystalline composition, optically anisotropic film, optical film, and polarizer and liquid-crystal display device using them | FUJIFILM CORPORATION (JP) | 2010-09-21 | — | — | US | disclosed |
| US-20080186443-A1 | Liquid Crystal Composition, Retardation Plate, and Elliptic Polarizing Plate | FUJIFILM CORPORATION (JP) | 2008-08-07 | — | — | US | disclosed |
| US-20080171143-A1 | Process For Preparation Of Optical Compensatory Sheet | FUJIFILM CORPORATION (JP) | 2008-07-17 | — | — | US | disclosed |
| US-20080169448-A1 | Liquid crystalline compound, liquid crystalline composition and retardation film | FUJIFILM CORPORATION (JP) | 2008-07-17 | — | — | US | disclosed |
| US-20080158483-A1 | Cellulose Acylate Film, Optical Compensation Film, Polarizing Plate, and Liquid Crystal Display Device | FUJIFILM CORPORATION (JP) | 2008-07-03 | — | — | US | disclosed |
| US-7361451-B2 | Lithographic printing plate precursor and lithographic printing method using the same | FUJIFILM CORPORATION (JP) | 2008-04-22 | — | — | US | disclosed |
| US-20070229740-A1 | Optical compensation film, polarizing plate and liquid crystal display device | FUJIFILM CORPORATION (JP) | 2007-10-04 | — | — | US | disclosed |
| US-7250116-B2 | Liquid crystal composition, polymerization product, retardation plate and ellipsoidally polarizing plate | FUJIFILM CORPORATION (JP) | 2007-07-31 | — | — | US | disclosed |
| US-20070132139-A1 | Process for preparation of optically anisotropic cellulose ester film | FUJI PHOTO FILM CO., LTD. | 2007-06-14 | — | — | US | disclosed |
| US-20070098920-A1 | Optical film, polarizing plate and liquid crystal display | FUJIFILM CORPORATION (JP) | 2007-05-03 | — | — | US | disclosed |
| US-20070002232-A1 | Optical compensation film, polarizing plate and liquid crystal display device | FUJI PHOTO FILM CO., LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080169448-A1 | Liquid crystalline compound, liquid crystalline composition and retardation film | NCAPD2, RCC1, CCND2 | OPRM1 4303/4885OPRD1 3025/4885UHRF1 1927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.