SCHEMBL10045971

SCHEMBL10045971

Cc1cc2[nH]c3cc4[nH]c5cc(C)c(C)cc5[nH]c4cc3[nH]c2cc1C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 3/20 0.63
GRIN3B O60391 3/20 0.63
GRIN1 Q05586 3/20 0.63
GRIN2A Q12879 3/20 0.63
GRIN2B Q13224 3/20 0.63
GRIN2C Q14957 3/20 0.63
GRIN3A Q8TCU5 3/20 0.63
KDM4E B2RXH2 2/20 0.63
ALDH1A1 P00352 1/20 0.63
HPGD P15428 1/20 0.63
FABP6 P51161 1/20 0.42
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
KMT2A Q03164 2/20 0.41
ATM Q13315 2/20 0.41
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41
MCL1 Q07820 1/20 0.41
GRIA1 P42261 1/20 0.41
GRIA2 P42262 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13953176 0.80 KDM4E (0.50) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL31487811 0.78 ALDH1A1 (1.00) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL121942 0.78 GRIN2D (1.00) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL762964 0.78 GRIN2D (0.70) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL15985685 0.67 KIF11 (0.64) KDM4EALDH1A1HPGDMEN1MAPT
SCHEMBL5039937 0.67 KEAP1 (0.44) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL39444 0.66 TSHR (0.57) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL24335067 0.66 AHR (0.48) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1105191 0.66 OPRM1 (0.51) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL1170803 0.64 FABP6 (0.63) KDM4EFABP6MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8283659-B2 Tetrahydrotetraazapentacenes in thin-film transistors XEROX CORPORATION (US) 2012-10-09 US disclosed
US-20120161108-A1 TETRAHYDROTETRAAZAPENTACENES IN THIN-FILM TRANSISTORS XEROX CORPORATION (US) 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120161108-A1 TETRAHYDROTETRAAZAPENTACENES IN THIN-FILM TRANSISTORS CYP4Z1, TCF4, TERT GRIN2D 173/4885GRIN3B 493/4885GRIN1 137/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.