Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045822 | 0.93 | MEN1 (0.43) | MEN1KMT2AKDM4ENPY1RRECQL | |
| SCHEMBL11043214 | 0.91 | ACE (0.42) | KMT2AACE | |
| SCHEMBL11051577 | 0.88 | ACE (0.47) | ACE | |
| SCHEMBL11045994 | 0.84 | TDP1 (0.36) | KMT2AACE | |
| SCHEMBL11046064 | 0.83 | ACE (0.42) | ACE | |
| SCHEMBL11052123 | 0.80 | MEN1 (0.32) | MEN1KMT2AACE | |
| SCHEMBL11043199 | 0.78 | ACE (0.55) | ACE | |
| SCHEMBL11047965 | 0.78 | ACE (0.55) | ACE | |
| SCHEMBL11050573 | 0.77 | KMT2A (0.49) | KMT2AACE | |
| SCHEMBL11047882 | 0.77 | KMT2A (0.49) | KMT2AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461896-A | 1-[Acylthio) and (mercapto)-1-oxoalkyl]-1,2,3,4-tetrahydroquinoline-2-carboxylic acids | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1984-07-24 | — | — | US | disclosed |