Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568676 | 1.00 | SLC18A3 (0.43) | SLC18A3HTR2BHTR2CHTR2ASLC6A2 | |
| SCHEMBL11052131 | 1.00 | SLC18A3 (0.43) | SLC18A3HTR2BHTR2CHTR2ASLC6A2 | |
| SCHEMBL11368333 | 0.89 | HTR1A (0.39) | HTR2BHTR2CHTR2ASLC6A2SLC6A4 | |
| SCHEMBL11368331 | 0.89 | HTR1A (0.39) | HTR2BHTR2CHTR2ASLC6A2SLC6A4 | |
| SCHEMBL22506859 | 0.88 | SLC18A3 (0.40) | SLC18A3HTR2BHTR2CSLC6A2ADRA2C | |
| SCHEMBL11359449 | 0.85 | HTR2C (0.42) | HTR2BHTR2CHTR2ASLC6A2POLB | |
| SCHEMBL11359447 | 0.85 | HTR2C (0.42) | HTR2BHTR2CHTR2ASLC6A2POLB | |
| SCHEMBL11360178 | 0.84 | — | — | |
| SCHEMBL11360175 | 0.84 | — | — | |
| SCHEMBL11369801 | 0.82 | HTR2C (0.40) | HTR2BHTR2CHTR2ASLC6A2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200321533-A1 | COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS | THE SCRIPPS RESEARCH INSTITUTE | 2020-10-08 | — | — | US | disclosed |
| US-4432978-A | NEUROLEPTIC AGENTS, TRANQUILIZERS | PFIZER INC. (US) | 1984-02-21 | — | — | US | disclosed |
| US-4431649-A | TRANQUILIZERS | PFIZER INC. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4431646-A | TRANQUILIZERS; PSYCHOSIS; NERVOUS SYSTEM DISORDERS | PFIZER INC. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4427679-A | TRANQUILIZERS; PSYCHOLOGICAL DISORDERS | PFIZER INC. (US) | 1984-01-24 | — | — | US | disclosed |
| US-4337250-A | NEUROLEPTIC AGENTS | PFIZER INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4277404-A | INTERMEDIATES FOR TRANQUILIZERS | PFIZER INC. (US) | 1981-07-07 | — | — | US | disclosed |
| US-4267331-A | REDUCTIVE ALKYLATION OF A 5-PHENYL-2,3,4,4A,5,9B-HEXAHYDRO-1H-PYRIDO/4,3-B/INDOLE WITH A REDUCING AGENT AND A 2-HYDROXY-5- OR 6-PHENYLFURAN OR -PYRAN | PFIZER INC. (US) | 1981-05-12 | — | — | US | disclosed |
| US-4252812-A | TRANQUILIZERS | PFIZER INC. (US) | 1981-02-24 | — | — | US | disclosed |
| US-4224329-A | TRANQUILIZERS | PFIZER INC. (US) | 1980-09-23 | — | — | US | disclosed |
| US-4174453-A | HYDROGENATION, ACIDFICATION | ENDO LABORATORIES, INC. (US) | 1979-11-13 | — | — | US | disclosed |
| US-3991199-A | ANALGESICS AND SEDATIVES | ENDO LABORATORIES, INC. (US) | 1976-11-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200321533-A1 | COMPOUNDS FOR ORGANIC LIGHT EMITTING DIODE MATERIALS | ALDH1A2, DDT, CLTB | SLC18A3 1904/4885HTR2B 544/4885HTR2C 993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.