Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11051641 | 0.83 | MAPT (0.40) | ALDH1A1GLATSHRKMT2ALMNA | |
| SCHEMBL11076701 | 0.81 | HTT (0.49) | ALDH1A1GLATSHRKMT2AHTT | |
| SCHEMBL7151140 | 0.74 | KMT2A (0.44) | ALDH1A1GLATSHRKMT2ALMNA | |
| SCHEMBL17536667 | 0.74 | KMT2A (0.44) | ALDH1A1GLATSHRKMT2ALMNA | |
| SCHEMBL11052732 | 0.74 | KMT2A (0.46) | ALDH1A1GLATSHRKMT2AHTT | |
| SCHEMBL9229562 | 0.69 | KMT2A (0.43) | ALDH1A1GLATSHRKMT2AHTT | |
| SCHEMBL28682647 | 0.69 | KMT2A (0.43) | ALDH1A1GLATSHRKMT2AHTT | |
| SCHEMBL10352835 | 0.69 | RIPK1 (0.50) | ALDH1A1TSHRKMT2ALMNAMEN1 | |
| SCHEMBL2231434 | 0.69 | KMT2A (0.46) | ALDH1A1GLATSHRKMT2AHTT | |
| SCHEMBL102609 | 0.67 | ALOX15 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443474-A | ANTICONVULSANT, ADMINISTERING | BUFFALO COLOR CORPORATION (US) | 1984-04-17 | — | — | US | claimed |
| US-4443474-A | ANTICONVULSANT, ADMINISTERING | BUFFALO COLOR CORPORATION (US) | 1984-04-17 | — | — | US | disclosed |