Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.57 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11047821 | 0.83 | MAPT (0.62) | GAADRD2DRD3MAPTPOLB | |
| SCHEMBL11052244 | 0.81 | DRD2 (0.67) | GAADRD2DRD3MAPTPOLB | |
| SCHEMBL11049712 | 0.80 | GAA (0.68) | GAAMAPTPOLBMEN1USP2 | |
| SCHEMBL26238627 | 0.79 | DRD2 (0.49) | GAADRD2MAPTTP53MEN1 | |
| SCHEMBL11048848 | 0.78 | DRD2 (0.71) | GAADRD2DRD3MAPTPOLB | |
| SCHEMBL7339643 | 0.78 | GAA (1.00) | GAADRD2DRD3MAPTPOLB | |
| SCHEMBL7339654 | 0.78 | GAA (1.00) | GAADRD2DRD3MAPTPOLB | |
| SCHEMBL11056826 | 0.78 | MAPT (0.62) | GAADRD2DRD3MAPTPOLB | |
| SCHEMBL6771493 | 0.78 | DRD2 (0.67) | GAADRD2DRD3MAPTPOLB | |
| SCHEMBL10401826 | 0.77 | DRD2 (0.62) | GAADRD2DRD3MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446133-A | ANTIARTHRITIC AGENTS | Misuitoatsu Chemicals, Inc. (JP) | 1984-05-01 | — | — | US | disclosed |