Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CFD | P00746 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11054307 | 0.87 | GRIN2D (0.42) | KDM4EALDH1A1GAAPOLBCFD | |
| SCHEMBL10318742 | 0.84 | KDM4E (0.64) | KDM4EALDH1A1GAAPOLBGRIN2D | |
| SCHEMBL14169498 | 0.80 | GPR35 (0.54) | KDM4EALDH1A1GAAHSD17B10HPGD | |
| SCHEMBL10318875 | 0.78 | KDM4E (0.59) | KDM4EALDH1A1GAAPOLBGRIN2D | |
| SCHEMBL10321066 | 0.77 | KDM4E (0.52) | KDM4EALDH1A1GAAPOLBGRIN2D | |
| SCHEMBL18359492 | 0.77 | KDM4E (0.58) | KDM4EALDH1A1GAAPOLBGRIN2D | |
| SCHEMBL8828077 | 0.76 | KDM4E (0.58) | KDM4EALDH1A1GAAPOLBGRIN2D | |
| SCHEMBL10318325 | 0.74 | ALDH1A1 (0.52) | KDM4EALDH1A1GAAPOLBGRIN2D | |
| SCHEMBL10319010 | 0.74 | ALDH1A1 (0.52) | KDM4EALDH1A1GAAPOLBGRIN2D | |
| SCHEMBL4414669 | 0.72 | CNR2 (0.57) | KDM4EALDH1A1GAAPOLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4468394-A | Cephalosporin compounds | EISAI CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| EP-0062328-A2 | Novel penicillin and cephalosporin compounds, a process for preparing the same and antibacterial composition containing the novel compounds | Eisai Co., Ltd. (JP) | 1982-10-13 | — | — | EP | disclosed |