Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10330642 | 0.79 | DAO (0.63) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL10969986 | 0.79 | KDM4E (0.66) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL8828102 | 0.79 | KDM4E (0.53) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL14128774 | 0.79 | GRIA1 (0.53) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL10318742 | 0.78 | KDM4E (0.64) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL585033 | 0.76 | KDM4E (0.54) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL4067945 | 0.76 | HSD17B10 (0.61) | KDM4EHSD17B10HPGDALDH1A1POLB | |
| SCHEMBL11052835 | 0.76 | KDM4E (0.54) | KDM4EHSD17B10HPGDGAAALDH1A1 | |
| SCHEMBL7682186 | 0.76 | GPR35 (0.63) | KDM4EHSD17B10HPGDALDH1A1MAPT | |
| SCHEMBL10318875 | 0.74 | KDM4E (0.59) | KDM4EHSD17B10HPGDGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646132-A | TREATING CEREBRAL ISCHEMIA | ADIR ET COMPAGNIE (FR) | 1997-07-08 | — | — | US | disclosed |
| US-5536709-A | INHIBITORS OF HYPERACTIVATION OF EXCITATORY AMINO ACIDS | ADIR ET COMPAGNIE (FR) | 1996-07-16 | — | — | US | disclosed |