Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | HTT | P42858 | 5/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RNF4 | P78317 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5381724 | 0.82 | ALDH1A1 (0.66) | ALDH1A1RAB9ANPC1HTTPAX8 | |
| SCHEMBL7102909 | 0.81 | PTPN7 (0.42) | ALDH1A1SMN1; SMN2KMT2APOLBPTPN7 | |
| SCHEMBL8852613 | 0.77 | INSR (0.49) | ALDH1A1HTTSMN1; SMN2KMT2ANPSR1 | |
| SCHEMBL11503414 | 0.77 | ALDH1A1 (0.49) | ALDH1A1RAB9ANPC1HTTPAX8 | |
| SCHEMBL9133855 | 0.75 | MTNR1A (0.51) | ALDH1A1RAB9ANPC1HTTPAX8 | |
| SCHEMBL7191809 | 0.74 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2KMT2APTPN7MEN1 | |
| SCHEMBL11739827 | 0.74 | NPC1 (0.49) | ALDH1A1RAB9ANPC1HTTPAX8 | |
| SCHEMBL28758819 | 0.74 | UTS2R (0.46) | ALDH1A1RAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL11787571 | 0.74 | RNF4 (0.63) | ALDH1A1RAB9ANPC1HTTPAX8 | |
| SCHEMBL10982478 | 0.72 | BCL2L1 (0.43) | ALDH1A1RAB9ANPC1HTTPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490370-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| EP-0122155-A2 | Improvements in or relating to naphthylglycyl cephalosporin derivatives | ELI LILLY AND COMPANY (US) | 1984-10-17 | — | — | EP | disclosed |