Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11057314 | 0.99 | MAPT (0.57) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL11057335 | 0.88 | USP2 (0.51) | MAPTALDH1A1KMT2AKDM4EHTR1A | |
| SCHEMBL11051683 | 0.85 | ALDH1A1 (0.55) | MAPTALDH1A1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL11057047 | 0.84 | ALDH1A1 (0.58) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL11059226 | 0.84 | AKR1C3 (0.54) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11051087 | 0.84 | HRH3 (0.57) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11053793 | 0.83 | MAPT (0.53) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL11051848 | 0.83 | HRH3 (0.56) | MAPTALDH1A1KMT2AMEN1HTR1A | |
| SCHEMBL1483601 | 0.83 | MAPT (0.63) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL11051109 | 0.82 | HRH3 (0.54) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446133-A | ANTIARTHRITIC AGENTS | Misuitoatsu Chemicals, Inc. (JP) | 1984-05-01 | — | — | US | disclosed |