Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PDE6D | O43924 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11053793 | 0.88 | MAPT (0.53) | ALDH1A1MAPTKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL11057335 | 0.85 | USP2 (0.51) | ALDH1A1MAPTKMT2ATSHRLMNA | |
| SCHEMBL11052895 | 0.85 | MAPT (0.58) | ALDH1A1MAPTKMT2ASMN1; SMN2HTT | |
| SCHEMBL11055041 | 0.83 | L3MBTL1 (0.62) | ALDH1A1MAPTKMT2AHTTLMNA | |
| Hydrochloric Acid SCHEMBL11057314 | 0.83 | MAPT (0.57) | ALDH1A1MAPTKMT2ASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL11050970 | 0.82 | L3MBTL1 (0.61) | ALDH1A1MAPTKMT2AHTTLMNA | |
| SCHEMBL4116463 | 0.81 | MAPT (0.69) | ALDH1A1MAPTKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL11059226 | 0.80 | AKR1C3 (0.54) | ALDH1A1MAPTKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL11051087 | 0.80 | HRH3 (0.57) | ALDH1A1MAPTKMT2ASMN1; SMN2HTT | |
| SCHEMBL11057047 | 0.80 | ALDH1A1 (0.58) | ALDH1A1MAPTKMT2ATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446133-A | ANTIARTHRITIC AGENTS | Misuitoatsu Chemicals, Inc. (JP) | 1984-05-01 | — | — | US | disclosed |