Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11051087 | 0.85 | HRH3 (0.57) | AKR1C3HTR1AMAPTALDH1A1LMNA | |
| SCHEMBL11057047 | 0.85 | ALDH1A1 (0.58) | AKR1C3HTR1AMAPTALDH1A1POLB | |
| SCHEMBL11051848 | 0.84 | HRH3 (0.56) | AKR1C3HTR1AMAPTALDH1A1POLB | |
| SCHEMBL11057335 | 0.84 | USP2 (0.51) | HTR1AMAPTALDH1A1POLBGAA | |
| SCHEMBL11052895 | 0.84 | MAPT (0.58) | HTR1AMAPTALDH1A1POLBLMNA | |
| Hydrochloric Acid SCHEMBL11051109 | 0.83 | HRH3 (0.54) | AKR1C3HTR1AMAPTALDH1A1POLB | |
| SCHEMBL30508269 | 0.83 | AKR1C3 (0.58) | AKR1C3MAPTALDH1A1POLBGAA | |
| Hydrochloric Acid SCHEMBL11057314 | 0.82 | MAPT (0.57) | HTR1AMAPTALDH1A1POLBLMNA | |
| SCHEMBL11055041 | 0.82 | L3MBTL1 (0.62) | AKR1C3MAPTALDH1A1POLBGAA | |
| Hydrochloric Acid SCHEMBL11050970 | 0.81 | L3MBTL1 (0.61) | AKR1C3MAPTALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446133-A | ANTIARTHRITIC AGENTS | Misuitoatsu Chemicals, Inc. (JP) | 1984-05-01 | — | — | US | disclosed |