Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | PRKCG | P05129 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PRKCB | P05771 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982630 | 0.85 | GPR35 (0.72) | ADORA2AADORA1ADORA3ALDH1A1LMNA | |
| SCHEMBL11344137 | 0.80 | MAOA (0.73) | ADORA2AADORA1ADORA3ALDH1A1LMNA | |
| SCHEMBL30969168 | 0.79 | MAOA (0.53) | ADORA2AADORA1ADORA3ALDH1A1LMNA | |
| SCHEMBL22132743 | 0.78 | MAOA (0.56) | ADORA2AADORA1ADORA3ALDH1A1LMNA | |
| SCHEMBL22132756 | 0.78 | MAOA (0.65) | ADORA2AADORA1ADORA3ALDH1A1LMNA | |
| SCHEMBL22129780 | 0.78 | MAOA (0.72) | ADORA2AADORA1ADORA3ALDH1A1LMNA | |
| SCHEMBL30969182 | 0.78 | ADORA2A (0.48) | ADORA2AADORA1ADORA3ALDH1A1LMNA | |
| SCHEMBL30969178 | 0.78 | MAOA (0.65) | ADORA2AADORA1ADORA3ALDH1A1LMNA | |
| SCHEMBL2792438 | 0.78 | HPGD (0.62) | ADORA2AADORA1ADORA3ALDH1A1LMNA | |
| SCHEMBL30969198 | 0.77 | GPR35 (0.45) | ADORA2AADORA1ADORA3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4468394-A | Cephalosporin compounds | EISAI CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4415567-A | A 7B-CHROMONE-3-CARBOXAMIDO-2-/4-HYDROXY PHENYL/ACETAMIDO-2-CEPHEM DERIVATIVE | EISAI CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |
| EP-0062328-A2 | Novel penicillin and cephalosporin compounds, a process for preparing the same and antibacterial composition containing the novel compounds | Eisai Co., Ltd. (JP) | 1982-10-13 | — | — | EP | disclosed |
| US-4344944-A | 7-α-methoxycephalosporin derivatives, and antibacterial drugs onctaining the same | EISAI CO., LTD. (JP) | 1982-08-17 | — | — | US | disclosed |
| US-4285940-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |
| US-4285941-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |
| US-4285939-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |