Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.65 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.58 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MIF | P14174 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PRKCG | P05129 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PRKCB | P05771 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22132756 | 1.00 | MAOA (0.65) | MAOAADORA2AADORA1ADORA3MAOB | |
| SCHEMBL30969203 | 0.89 | MAOA (0.53) | MAOAADORA2AADORA1ADORA3MAOB | |
| SCHEMBL30969168 | 0.89 | MAOA (0.53) | MAOAADORA2AADORA1ADORA3MAOB | |
| SCHEMBL30969169 | 0.89 | MEN1 (0.64) | MAOAADORA2AADORA1ADORA3MAOB | |
| SCHEMBL22129780 | 0.88 | MAOA (0.72) | MAOAADORA2AADORA1ADORA3MAOB | |
| SCHEMBL22132754 | 0.85 | PKM (0.66) | MAOAMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL30969186 | 0.85 | PKM (0.66) | MAOAMAOBMEN1KMT2AALDH1A1 | |
| SCHEMBL22132753 | 0.85 | MAOA (0.63) | MAOAADORA2AADORA1ADORA3MAOB | |
| SCHEMBL982630 | 0.80 | GPR35 (0.72) | MAOAADORA2AADORA1ADORA3MAOB | |
| SCHEMBL22132743 | 0.79 | MAOA (0.56) | MAOAADORA2AADORA1ADORA3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118206520-A | Coumarin derivatives, application and ACLY inhibitor and related diseases | 中国科学院大连化学物理研究所 | 2024-06-18 | — | — | CN | claimed |
| CN-118206520-A | Coumarin derivatives, application and ACLY inhibitor and related diseases | 中国科学院大连化学物理研究所 | 2024-06-18 | — | — | CN | disclosed |