Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | ADH1B | P00325 | 2/20 | 0.39 |
| ▸ | ADH1C | P00326 | 2/20 | 0.39 |
| ▸ | ADH1A | P07327 | 2/20 | 0.39 |
| ▸ | ADH4 | P08319 | 2/20 | 0.39 |
| ▸ | ADH7 | P40394 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TOP1 | P11387 | 2/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.32 |
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL150653 | 1.00 | TSHR (0.48) | TSHRFAAHTRPV1ADH1BADH1C | |
| SCHEMBL5680694 | 1.00 | TSHR (0.48) | TSHRFAAHTRPV1ADH1BADH1C | |
| SCHEMBL152136 | 0.90 | — | — | |
| SCHEMBL1653708 | 0.79 | — | — | |
| SCHEMBL5552653 | 0.79 | TSHR (0.58) | TSHRFAAHTRPV1ADH1BADH1C | |
| SCHEMBL8602710 | 0.76 | TSHR (0.48) | TSHRFAAHTHRB | |
| SCHEMBL11041293 | 0.76 | TSHR (0.57) | TSHREPHX1THRB | |
| SCHEMBL10317806 | 0.76 | TSHR (0.57) | TSHREPHX1THRB | |
| SCHEMBL6234379 | 0.76 | TSHR (0.57) | TSHREPHX1THRB | |
| SCHEMBL152301 | 0.76 | TSHR (0.57) | TSHREPHX1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451688-A | Process for preparing polyolefins | NIPPON OIL COMPANY, LIMITED (JP) | 1984-05-29 | — | — | US | disclosed |