SCHEMBL150653

SCHEMBL150653

CCCCCC[Mg]CC=O

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
FAAH O00519 2/20 0.43
TRPV1 Q8NER1 2/20 0.43
ADH1B P00325 2/20 0.39
ADH1C P00326 2/20 0.39
ADH1A P07327 2/20 0.39
ADH4 P08319 2/20 0.39
ADH7 P40394 2/20 0.39
EPHX1 P07099 1/20 0.39
THRB P10828 1/20 0.38
TOP1 P11387 2/20 0.32
TRPM8 Q7Z2W7 4/20 0.32
CES2 O00748 2/20 0.32
CES1 P23141 2/20 0.32
EPHX2 P34913 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11053276 1.00 TSHR (0.48) TSHRFAAHTRPV1ADH1BADH1C
SCHEMBL5680694 1.00 TSHR (0.48) TSHRFAAHTRPV1ADH1BADH1C
SCHEMBL152136 0.90
SCHEMBL1653708 0.79
SCHEMBL5552653 0.79 TSHR (0.58) TSHRFAAHTRPV1ADH1BADH1C
SCHEMBL8602710 0.76 TSHR (0.48) TSHRFAAHTHRB
SCHEMBL11041293 0.76 TSHR (0.57) TSHREPHX1THRB
SCHEMBL10317806 0.76 TSHR (0.57) TSHREPHX1THRB
SCHEMBL6234379 0.76 TSHR (0.57) TSHREPHX1THRB
SCHEMBL152301 0.76 TSHR (0.57) TSHREPHX1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 400 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3969490-B1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND TIRE COMPONENTS BRIDGESTONE CORP (JP) 2026-03-25 EP disclosed
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-12-25 US disclosed
US-12479935-B2 Polymerization processes for the production of cis-1,4-polydienes BRIDGESTONE CORPORATION (JP) 2025-11-25 US disclosed
US-12410263-B2 Modified high-Cis polybutadiene polymer, related methods and rubber compositions BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-09-09 US disclosed
US-12371516-B2 Aged lanthanide-based catalyst systems and their use in the preparation of cis-1,4-polydienes BRIDGESTONE CORPORATION (JP) 2025-07-29 US disclosed
US-12264232-B2 Modified high-cis polybutadiene polymer, related methods and tire components BRIDGESTONE CORPORATION (JP) 2025-04-01 US disclosed
US-20250066516-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME BRIDGESTONE CORPORATION (JP) 2025-02-27 US disclosed
EP-4495146-A2 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS Bridgestone Americas Tire Operations, LLC (US) 2025-01-22 EP disclosed
US-12168705-B2 Modified high cis polydiene polymer, related methods and rubber compositions BRIDGESTONE CORPORATION (JP) 2024-12-17 US disclosed
EP-4457250-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME Bridgestone Corporation (JP) 2024-11-06 EP disclosed
EP-1242482-A1 IRON-BASED CATALYST FOR PRODUCING BINARY CIS-1,4-/1,2-POLYBUTADIENE Bridgestone Corporation (JP) 2002-09-25 EP disclosed
WO-2002068484-A1 CONTINUOUS PROCESS FOR THE PRODUCTION OF CONJUGATED DIENE POLYMERS HAVING NARROW MOLECULAR WEIGHT DISTRIBUTION AND PRODUCTS THEREFROM BRIDGESTONE CORPORATION (JP) 2002-09-06 WO disclosed
WO-2002066525-A1 CHROMIUM-BASED CATALYST COMPOSITION BRIDGESTONE CORPORATION (JP) 2002-08-29 WO disclosed
US-20020115558-A1 CHROMIUM-BASED CATALYST COMPOSITION FOR PRODUCING CONJUGATED DIENE POLYMERS BRIDGESTONE CORP. 2002-08-22 US disclosed
US-20020037967-A1 Process for producing blends of syndiotactic 1,2-polybutadiene and rubbery elastomers with a chromium-based catalyst system BRIDGESTONE CORPORATION (JP) 2002-03-28 US disclosed
US-6320004-B1 FORMED BY COMBINING (A) A IRON-CONTAINING COMPOUND; (B) AN ORGANOMAGNESIUM COMPOUND; AND (C) A SILYL PHOSPHONATE; POLYMERIZING CONJUGATED DIENE MONOMERS BRIDGESTONE CORPORATION (JP) 2001-11-20 US disclosed
WO-2001079309-A2 USE OF A Cr- OR Mo-BASED CATALYST SYSTEM TO PRODUCE BLENDS OF SYNDIOTACTIC 1,2-POLYBUTADIENE AND RUBBERY ELASTOMERS BRIDGESTONE CORPORATION (JP) 2001-10-25 WO disclosed
US-6291591-B1 PROVIDING MIXTURE OF RUBBER CEMENT AND 1,3-BUTADIENE; POLYMERIZING 1,3-BUTADIENE BY USING A CATALYST WHICH IS COMBINATION OF OR THE REACTION PRODUCT OF CHROMIUM COMPOUND, HYDROGEN PHOSPHITE, ORGANOMAGNESIUM COMPOUND BRIDGESTONE CORPORATION (JP) 2001-09-18 US disclosed
WO-2001049755-A1 IRON-BASED CATALYST FOR PRODUCING BINARY Cis-1,4-/1,2-POLYBUTADIENE BRIDGESTONE CORPORATION (JP) 2001-07-12 WO disclosed
US-6160063-A Iron-based catalyst for producing binary cis-1,4-/1,2-polybutadiene BRIDGESTONE CORPORATION (JP) 2000-12-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS MALT1, INO80C, RTCB TSHR 1694/4885FAAH 2217/4885TRPV1 3429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.