SCHEMBL5680694

SCHEMBL5680694

CCCCCCCC[Mg]CC=O

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
FAAH O00519 2/20 0.43
TRPV1 Q8NER1 2/20 0.43
ADH1B P00325 2/20 0.39
ADH1C P00326 2/20 0.39
ADH1A P07327 2/20 0.39
ADH4 P08319 2/20 0.39
ADH7 P40394 2/20 0.39
EPHX1 P07099 1/20 0.39
THRB P10828 1/20 0.38
TOP1 P11387 2/20 0.32
TRPM8 Q7Z2W7 4/20 0.32
CES2 O00748 2/20 0.32
CES1 P23141 2/20 0.32
EPHX2 P34913 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL150653 1.00 TSHR (0.48) TSHRFAAHTRPV1ADH1BADH1C
SCHEMBL11053276 1.00 TSHR (0.48) TSHRFAAHTRPV1ADH1BADH1C
SCHEMBL152136 0.90
SCHEMBL1653708 0.79
SCHEMBL5552653 0.79 TSHR (0.58) TSHRFAAHTRPV1ADH1BADH1C
SCHEMBL8602710 0.76 TSHR (0.48) TSHRFAAHTHRB
SCHEMBL11041293 0.76 TSHR (0.57) TSHREPHX1THRB
SCHEMBL10317806 0.76 TSHR (0.57) TSHREPHX1THRB
SCHEMBL6234379 0.76 TSHR (0.57) TSHREPHX1THRB
SCHEMBL152301 0.76 TSHR (0.57) TSHREPHX1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747113-B1 CAST FILMS WHICH HAVE GOOD STRETCHABILITY AND GOOD PUNCTURE RESISTANCE. THE DOW CHEMICAL COMPANY 2004-06-08 US claimed
US-6172173-B1 AN UNBLENDED COPOLYMER COMPRISING ETHYLENE AND AT LEAST ONE C3 -C20 ALPHA OLEFIN COMONOMER POLYMERIZED IN PRESENCE OF A CATALYST SYSTEM CONTAINING INORGANIC OXIDE SUPPORT AND ORGANOMEGNESIUM ALKOXIDE AND TITANIUM COMPOUNDS THE DOW CHEMICAL COMPANY 2001-01-09 US claimed
EP-0705282-B1 Use of the variation of the ratio of Mg:Ti in a catalyst to vary or control the short chain branching distribution of ethylene copolymers DOW CHEMICAL CO (US) 1998-07-29 EP claimed
EP-0705282-A1 Use of the variation of the ratio of Mg:Ti in a catalyst to vary or controll the short chain branching distribution of ethylene copolymers THE DOW CHEMICAL COMPANY (a Delaware corporation) (US) 1996-04-10 EP claimed
US-5420090-A Coordination catalysts for polymerization THE DOW CHEMICAL COMPANY (US) 1995-05-30 US claimed
EP-0567584-B1 SILICA SUPPORTED TRANSITION METAL CATALYST DOW CHEMICAL CO (US) 1994-12-28 EP claimed
EP-0567584-A1 SILICA SUPPORTED TRANSITION METAL CATALYST. DOW CHEMICAL CO (US) 1993-11-03 EP claimed
WO-1993019105-A2 SILICA SUPPORTED TRANSITION METAL CATALYST THE DOW CHEMICAL COMPANY (US) 1993-09-30 WO claimed
US-5231151-A Polymerization catalyst THE DOW CHEMICAL COMPANY (US) 1993-07-27 US claimed
WO-1992013009-A1 SILICA SUPPORTED TRANSITION METAL CATALYST THE DOW CHEMICAL COMPANY (US) 1992-08-06 WO claimed
US-4601994-A POLYMERIZATION CAATALYSTS THE DOW CHEMICAL COMPANY (US) 1986-07-22 US claimed
EP-0775163-B2 SUPPORTED OLEFIN POLYMERIZATION CATALYST DOW CHEMICAL CO (US) 2006-04-05 EP disclosed
US-20030050411-A1 Use of polar monomers in olefin polymerization and polymers thereof DOW GLOBAL TECHNOLOGIES INC. 2003-03-13 US disclosed
WO-2002100906-A1 USE OF POLAR MONOMERS IN OLEFIN POLYMERIZATION AND POLYMERS THEREOF DOW GLOBAL TECHNOLOGIES INC. (US) 2002-12-19 WO disclosed
US-6271164-B1 METALLOCENE CATALYST LYONDELL CHEMICAL TECHNOLOGY, L.P. 2001-08-07 US disclosed
US-5487938-A POLYMERIZATION CATALYSTS OF INORGANIC OXIDES ON SUPPORTS OF SILICA OR ALUMINA THE DOW CHEMICAL COMPANY (US) 1996-01-30 US disclosed
US-5420090-A Coordination catalysts for polymerization THE DOW CHEMICAL COMPANY (US) 1995-05-30 US disclosed
EP-0567584-B1 SILICA SUPPORTED TRANSITION METAL CATALYST DOW CHEMICAL CO (US) 1994-12-28 EP disclosed
US-5231151-A Polymerization catalyst THE DOW CHEMICAL COMPANY (US) 1993-07-27 US disclosed
WO-1992013009-A1 SILICA SUPPORTED TRANSITION METAL CATALYST THE DOW CHEMICAL COMPANY (US) 1992-08-06 WO disclosed