Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | STAT6 | P42226 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13620787 | 0.84 | — | — | |
| SCHEMBL16229099 | 0.79 | KDM4E (0.30) | — | |
| SCHEMBL1595375 | 0.78 | MAPK1 (0.31) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL3892012 | 0.78 | — | — | |
| SCHEMBL11532143 | 0.73 | TAS1R3 (0.34) | — | |
| SCHEMBL11603277 | 0.73 | — | — | |
| SCHEMBL5428847 | 0.73 | MAPK1 (0.42) | MAPK1TP53NFKB1CYP2C19THPO | |
| SCHEMBL11603677 | 0.72 | CYP1A2 (0.35) | — | |
| SCHEMBL5188257 | 0.70 | — | — | |
| Methyl Alcohol SCHEMBL4652953 | 0.70 | ALDH1A1 (0.36) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431577-A | TOBACCO; FOODS; PERFUMES; TOILETRIES; COSMETICS; DETERGENTS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4395366-A | Carbomethoxy methyl norbornanes, organoleptic uses thereof and process for preparing same | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1983-07-26 | — | — | US | disclosed |
| US-4350823-A | ORGANOLEPTIC AGENTS FOR INGESTIBLE PRODUCTS AND LAUNDRY ITEMS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1982-09-21 | — | — | US | disclosed |