Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19007315 | 0.82 | HTT (0.39) | ALDH1A1POLBGAATDP1HTT | |
| SCHEMBL18757121 | 0.82 | HCAR3 (0.36) | MAPTALDH1A1POLBGPR55TDP1 | |
| SCHEMBL23469288 | 0.78 | ALDH1A1 (0.38) | MAPTALDH1A1THRBGAANPSR1 | |
| SCHEMBL10111220 | 0.78 | ALDH1A1 (0.38) | MAPTALDH1A1POLBTHRBTDP1 | |
| SCHEMBL7997975 | 0.77 | ALDH1A1 (0.40) | MAPTALDH1A1THRBGAANPSR1 | |
| SCHEMBL7255765 | 0.76 | TP53 (0.44) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL21793456 | 0.72 | TDP1 (0.44) | ALDH1A1POLBTHRBGAATDP1 | |
| SCHEMBL3185975 | 0.72 | TDP1 (0.44) | ALDH1A1POLBTHRBGAATDP1 | |
| SCHEMBL11050700 | 0.71 | ALDH1A1 (0.48) | MAPTALDH1A1POLBTDP1HTT | |
| SCHEMBL9703394 | 0.71 | ALDH1A1 (0.39) | MAPTALDH1A1POLBGPR55THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439380-A | Photopolymerizable composition, especially for dental purposes | ETABLISSEMENT DENTAIRE IVOCLAR (LI) | 1984-03-27 | — | — | US | claimed |