Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.62 |
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | GLA | P06280 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SDHB | P21912 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6203180 | 0.75 | GABRA1 (0.48) | KDM4EALDH1A1GAAL3MBTL1HPGD | |
| SCHEMBL4425907 | 0.70 | ALDH1A1 (0.44) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL20266759 | 0.69 | ALDH1A1 (0.43) | KDM4EALDH1A1GAAHPGDTSHR | |
| SCHEMBL18358397 | 0.69 | ALDH1A1 (0.48) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL22004819 | 0.69 | TP53 (0.45) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL4548028 | 0.69 | KDM4E (0.58) | KDM4EALDH1A1GAAL3MBTL1HPGD | |
| SCHEMBL18195118 | 0.67 | KDM4E (0.55) | KDM4EALDH1A1GAAL3MBTL1HPGD | |
| SCHEMBL710035 | 0.67 | ALDH1A1 (0.43) | KDM4EALDH1A1GAAL3MBTL1HPGD | |
| SCHEMBL12807981 | 0.66 | MEN1 (0.53) | ALDH1A1MAPK1TSHRKMT2AMEN1 | |
| SCHEMBL27907538 | 0.64 | KDM4E (0.52) | KDM4EALDH1A1GAAL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444774-A | TRANQUILIZERS | AMERICAN CYANAMID COMPANY (US) | 1984-04-24 | — | — | US | disclosed |