Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28182923 | 0.83 | THRB (0.48) | CHRM1ALDH1A1CHRM2CHRM3CHRM4 | |
| SCHEMBL2720087 | 0.82 | MAOA (0.52) | KDM4ECHRM1ALDH1A1SMN1; SMN2CHRM2 | |
| Benzil SCHEMBL10781939 | 0.81 | EGFR (0.50) | CHRM1ALDH1A1SMN1; SMN2CHRM2CHRM3 | |
| Benzoic Acid SCHEMBL31179841 | 0.81 | POLB (0.55) | CHRM1ALDH1A1SMN1; SMN2CHRM2CHRM3 | |
| SCHEMBL28671752 | 0.81 | CHRM2 (0.54) | CHRM1ALDH1A1SMN1; SMN2CHRM2CHRM3 | |
| SCHEMBL14984 | 0.81 | CHRM2 (0.54) | CHRM1ALDH1A1SMN1; SMN2CHRM2CHRM3 | |
| SCHEMBL8084626 | 0.80 | CHRM1 (0.44) | KDM4ECHRM1ALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL6037217 | 0.80 | ALDH1A1 (0.50) | CHRM1ALDH1A1SMN1; SMN2LMNAMAPT | |
| Ammonia Solution, Strong SCHEMBL8139148 | 0.79 | CHRM2 (0.52) | CHRM1ALDH1A1SMN1; SMN2CHRM2CHRM3 | |
| Bromide SCHEMBL1255341 | 0.79 | CHRM2 (0.52) | CHRM1ALDH1A1SMN1; SMN2CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4437836-A | NONIRRITATING | BAYER AKTIENGESELLSCHAFT (DE) | 1984-03-20 | — | — | US | disclosed |