Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR1 | Q9BXC0 | 8/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648027 | 0.90 | — | — | |
| SCHEMBL14635395 | 0.82 | MAPT (0.39) | ALDH1A1KMT2AMAPTPKMSLC18A3 | |
| SCHEMBL11791511 | 0.69 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL4112401 | 0.69 | HCAR1 (0.50) | HCAR1 | |
| SCHEMBL12062407 | 0.67 | HCAR1 (0.49) | HCAR1 | |
| SCHEMBL18717642 | 0.62 | GFER (0.59) | HCAR1ALDH1A1SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL18611874 | 0.62 | ALDH1A1 (0.47) | HCAR1ALDH1A1SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL9322100 | 0.60 | GSK3A (0.38) | HCAR1ALDH1A1SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL7190295 | 0.60 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6235625 | 0.58 | OPRM1 (0.49) | ALDH1A1CYP2C9CYP2C19KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112279813-B | 1-cyclohexyl pyrazolone carboxylesterase 1 inhibitor, preparation and application thereof | 上海中医药大学 | 2023-02-28 | — | — | CN | claimed |
| CN-112279813-A | 1-cyclohexyl pyrazolone carboxylesterase 1 inhibitor, preparation and application thereof | 上海中医药大学 | 2021-01-29 | — | — | CN | claimed |
| CN-112279813-B | 1-cyclohexyl pyrazolone carboxylesterase 1 inhibitor, preparation and application thereof | 上海中医药大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-112279813-B | 1-cyclohexyl pyrazolone carboxylesterase 1 inhibitor, preparation and application thereof | 上海中医药大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-112279813-B | 1-cyclohexyl pyrazolone carboxylesterase 1 inhibitor, preparation and application thereof | 上海中医药大学 | 2023-02-28 | — | — | CN | disclosed |
| CN-112279813-A | 1-cyclohexyl pyrazolone carboxylesterase 1 inhibitor, preparation and application thereof | 上海中医药大学 | 2021-01-29 | — | — | CN | disclosed |
| US-4442202-A | SILVER HALIDE, REDOX SYSTEM, ORGANOBROMINE COMPOUND, STORAGE STABILITY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1984-04-10 | — | — | US | disclosed |
| US-4396712-A | ORGANIC SILVER SALT OXIDIZER, REDUCING AGENT, SILVER HALIDE OR SILVER HALIDE FORMER, TONER, BINDER, HYDROXYPHENYLBENZOTRIAZOLE | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1983-08-02 | — | — | US | disclosed |
| US-4332889-A | IMPROVED SENSITIVITY, STORAGE STABILITY | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1982-06-01 | — | — | US | disclosed |