1,2-Dimethoxybenzene

1,2-Dimethoxybenzene

SCHEMBL11054522

C=CCOCC=C.COc1ccccc1OC

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56
CA7 P43166 2/20 0.56
CA9 Q16790 2/20 0.56
CA12 O43570 1/20 0.56
CA4 P22748 1/20 0.56
CA14 Q9ULX7 1/20 0.56
ACHE P22303 2/20 0.50
ALDH1A1 P00352 3/20 0.46
PPARG P37231 1/20 0.46
PPARD Q03181 1/20 0.46
PPARA Q07869 1/20 0.46
L3MBTL1 Q9Y468 3/20 0.45
MAPK1 P28482 2/20 0.45
HTT P42858 1/20 0.45
KMT2A Q03164 2/20 0.41
TSHR P16473 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
TP53 P04637 1/20 0.41
ADRA2B P18089 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1-Allyloxy-2-Methoxybenzene SCHEMBL30083991 0.85 CA12 (0.54) CA1CA2CA7CA9CA12
1-Allyloxy-2-Methoxybenzene SCHEMBL73345 0.85 CA12 (0.54) CA1CA2CA7CA9CA12
SCHEMBL16949972 0.83 IDO1 (0.55) CA1CA2CA7CA9CA12
SCHEMBL2453030 0.82 NFE2L2 (0.49) ALDH1A1KMT2ATSHRPTGS1SMN1; SMN2
SCHEMBL2453028 0.82 NFE2L2 (0.49) ALDH1A1KMT2ATSHRPTGS1SMN1; SMN2
O-Xylene SCHEMBL2065413 0.77 TSHR (0.48) ACHEALDH1A1MAPK1HTTKMT2A
Naphthalene SCHEMBL8370666 0.77 CYP3A4 (0.43) ACHEALDH1A1MAPK1KMT2ATSHR
SCHEMBL6663936 0.76 HTR7 (0.53) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL27567930 0.75 CA1 (0.87) CA1CA2CA7CA9CA12
1,2-Dimethoxybenzene SCHEMBL29351917 0.75 CA1 (1.00) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0162263-A1 Process for the production of acetic acid from synthesis gas QUANTUM CHEMICAL CORPORATION (a Virginia corp.) (US) 1985-11-27 EP disclosed