Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NCEH1 | Q6PIU2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11056745 | 0.88 | SLC9A1 (0.45) | SLC9A1NPC1RAB9ANCEH1POLB | |
| SCHEMBL7600465 | 0.81 | SLC9A1 (0.51) | SLC9A1NCEH1HTTMEN1KMT2A | |
| SCHEMBL11057263 | 0.79 | NCEH1 (0.46) | NPC1RAB9ANCEH1POLBHTT | |
| SCHEMBL5762353 | 0.78 | LCK (0.56) | SLC9A1HTT | |
| SCHEMBL10391363 | 0.77 | KMT2A (0.47) | POLBMEN1KMT2AL3MBTL1TDP1 | |
| SCHEMBL11047891 | 0.75 | SLC9A1 (0.48) | SLC9A1NCEH1HTTMEN1KMT2A | |
| SCHEMBL12569622 | 0.75 | TDP1 (0.54) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL11169641 | 0.74 | L3MBTL1 (0.40) | NPC1RAB9ANCEH1POLBL3MBTL1 | |
| SCHEMBL12086947 | 0.74 | POLB (0.52) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL10390871 | 0.73 | MTNR1A (0.47) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447452-A | ANTIDIABETIC AGENT | AYERST, MCKENNA & HARRISON INC. (CA) | 1984-05-08 | — | — | US | disclosed |