Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.54 |
| ▸ | TRDMT1 | O14717 | 1/20 | 0.53 |
| ▸ | AHCY | P23526 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPEPPS | P55786 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ANPEP | P15144 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11054057 | 0.88 | TRDMT1 (0.59) | ADORA3TRDMT1AHCYSMN1; SMN2NPEPPS | |
| SCHEMBL11054481 | 0.88 | AHCY (0.60) | ADORA3TRDMT1AHCYADORA2BTSHR | |
| SCHEMBL11059822 | 0.86 | TRDMT1 (0.57) | TRDMT1AHCYSMN1; SMN2NPEPPSTP53 | |
| SCHEMBL10886529 | 0.85 | TRDMT1 (0.56) | TRDMT1AHCYSMN1; SMN2NPEPPSTP53 | |
| SCHEMBL10886428 | 0.84 | SMN1; SMN2 (0.65) | ADORA3TRDMT1AHCYSMN1; SMN2NPEPPS | |
| SCHEMBL11060597 | 0.83 | TRDMT1 (0.54) | TRDMT1AHCYSMN1; SMN2NPEPPSTP53 | |
| SCHEMBL10896379 | 0.83 | AHCY (0.54) | TRDMT1AHCYSMN1; SMN2NPEPPSTP53 | |
| SCHEMBL10884643 | 0.82 | AHCY (0.59) | TRDMT1AHCYSMN1; SMN2NPEPPSTP53 | |
| SCHEMBL10883715 | 0.82 | TRDMT1 (0.49) | ADORA3TRDMT1AHCYSMN1; SMN2NPEPPS | |
| SCHEMBL10884608 | 0.81 | TRDMT1 (0.51) | TRDMT1AHCYSMN1; SMN2NPEPPSTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |