Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRDMT1 | O14717 | 1/20 | 0.59 |
| ▸ | AHCY | P23526 | 6/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
| ▸ | NNMT | P40261 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPEPPS | P55786 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ANPEP | P15144 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059822 | 0.98 | TRDMT1 (0.57) | TRDMT1AHCYHIF1ATMEM97SIGMAR1 | |
| SCHEMBL10886529 | 0.95 | TRDMT1 (0.56) | TRDMT1AHCYHIF1ATMEM97SIGMAR1 | |
| SCHEMBL11060597 | 0.93 | TRDMT1 (0.54) | TRDMT1AHCYHIF1ATMEM97SIGMAR1 | |
| SCHEMBL10884643 | 0.92 | AHCY (0.59) | TRDMT1AHCYHIF1ATMEM97SIGMAR1 | |
| SCHEMBL10886849 | 0.91 | TRDMT1 (0.51) | TRDMT1AHCYHIF1ATMEM97SIGMAR1 | |
| SCHEMBL10884608 | 0.91 | TRDMT1 (0.51) | TRDMT1AHCYHIF1ATMEM97SIGMAR1 | |
| SCHEMBL11053230 | 0.90 | TRDMT1 (0.52) | TRDMT1AHCYHIF1ATMEM97SIGMAR1 | |
| SCHEMBL10884690 | 0.89 | TRDMT1 (0.49) | TRDMT1AHCYHIF1ANNMTATM | |
| SCHEMBL11054702 | 0.88 | ADORA3 (0.54) | TRDMT1AHCYHIF1AATMSMN1; SMN2 | |
| SCHEMBL10887916 | 0.88 | AHCY (0.54) | TRDMT1AHCYHIF1ANNMTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |