SCHEMBL1105476

SCHEMBL1105476

COc1ccc(CCCC(C)=O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.68
F2RL1 P55085 1/20 0.61
CALM1 P0DP23 1/20 0.59
SMN1; SMN2 Q16637 2/20 0.58
CYP1A2 P05177 2/20 0.58
CYP3A4 P08684 2/20 0.58
KDM4E B2RXH2 1/20 0.58
NPC1 O15118 1/20 0.58
LMNA P02545 1/20 0.58
TP53 P04637 1/20 0.58
MAPT P10636 1/20 0.58
MAOA P21397 1/20 0.58
SLC6A2 P23975 1/20 0.58
RAB9A P51151 1/20 0.58
SLC6A3 Q01959 1/20 0.58
ALDH1A1 P00352 1/20 0.57
POLB P06746 1/20 0.57
PLAAT3 P53816 1/20 0.55
PLAAT5 Q96KN8 1/20 0.55
PLAAT2 Q9NWW9 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13498520 0.95 ALOX5 (0.61) ALOX5F2RL1CALM1SMN1; SMN2CYP1A2
SCHEMBL9235000 0.93 ALOX5 (0.59) ALOX5F2RL1CALM1SMN1; SMN2CYP1A2
SCHEMBL11637942 0.93 ALOX5 (0.59) ALOX5F2RL1CALM1SMN1; SMN2CYP1A2
SCHEMBL8003026 0.93 ALOX5 (0.59) ALOX5F2RL1CALM1SMN1; SMN2CYP1A2
SCHEMBL2468017 0.89 SMN1; SMN2 (0.72) ALOX5F2RL1SMN1; SMN2CYP1A2CYP3A4
SCHEMBL1334 0.89 SMN1; SMN2 (0.72) ALOX5F2RL1SMN1; SMN2CYP1A2CYP3A4
SCHEMBL9574216 0.86 TDP1 (0.54) ALOX5F2RL1CALM1SMN1; SMN2CYP1A2
SCHEMBL503646 0.85 ALOX5 (0.68) ALOX5F2RL1CALM1SMN1; SMN2CYP1A2
SCHEMBL659052 0.85 ALOX5 (0.68) ALOX5F2RL1CALM1ALDH1A1POLB
SCHEMBL17288829 0.85 CYP1A2 (0.82) ALOX5SMN1; SMN2CYP1A2CYP3A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120117981-A Method for preparing mono-fatty glyceride by cucurbituril acid enrichment 四川大学 2025-06-10 CN disclosed
CN-117897439-A Method for screening solvent for extraction of polyvinyl chloride, method for recovering waste material, and recovered polyvinyl chloride and composition 株式会社LG化学 2024-04-16 CN disclosed
CN-113490659-B Improved and economically viable process for preparing aryl ketones 安西娅芳香剂私人有限公司 2024-03-29 CN disclosed
WO-2022032353-A1 RADIOPHARMACEUTICALS, USES THEREOF, AND METHODS FOR THE PRODUCTION THEREOF Clarity Pharmaceuticals Ltd (AU) 2022-02-17 WO disclosed
CN-110382575-A ACTIVE ENERGY RAY-CURABLE RESIN COMPOSITION AND COATING AGENT 三菱化学株式会社 2019-10-25 CN disclosed
CN-109879788-A A method of preparing N- substituted indole derivative 兰州大学 2019-06-14 CN disclosed
CN-105859496-B A kind of green synthesis method of acetal or ketal compounds 合肥工业大学 2019-01-11 CN disclosed
CN-108719500-A A kind of preparation method of Zanthoxylum essential oil 刘宁忠 2018-11-02 CN disclosed
CN-105859496-A Green synthesis method of acetal-type or ketal-type compound 合肥工业大学 2016-08-17 CN disclosed
CN-102971098-B Manufacturing method of casting mold ASAHI ORGANIC CHEM IND 2015-01-07 CN disclosed
US-20080269221-A1 ANTIBACTERIAL AGENTS NOVARTIS VACCINES AND DIAGNOSTICS, INC. 2008-10-30 US disclosed
US-7358359-B2 Antibacterial agents UNIVERSITY OF WASHINGTON (US) 2008-04-15 US disclosed
US-7358359-B2 Antibacterial agents UNIVERSITY OF WASHINGTON (US) 2008-04-15 US disclosed
US-20070244197-A1 Antibacterial agents UNIVERSITY OF WASHINGTON (US) 2007-10-18 US disclosed
US-20070244197-A1 Antibacterial agents UNIVERSITY OF WASHINGTON (US) 2007-10-18 US disclosed
US-4751246-A ALPHA(AMINOALKYL)-4-HYDROXY-3-(ALKYLSULFINYL) BENZENEMETHANOL AND 2-(4-HYDROXY-3-(ALKYLSULFINYL) PHENYL)ETHYLAMINE-HYPOTENSIVE AGENTS STERLING DRUG INC. (US) 1988-06-14 US disclosed
EP-0267439-A2 Alpha-(phenylalkyl) pyridinealkanol derivatives G.D. Searle & Co. (US) 1988-05-18 EP disclosed
US-4695589-A HYPOTENSIVE AGENTS STERLING DRUG INC. (US) 1987-09-22 US disclosed
US-4452816-A HYPOTENSIVE AND ANTIARRHYTHMIA AGENTS STERLING DRUG INC. (US) 1984-06-05 US disclosed
US-4374149-A HYPOTENSIVE AGENT AND VASODILATOR STERLING DRUG INC. (US) 1983-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070244197-A1 Antibacterial agents MRPL21, SI, PGLS ALOX5 1393/4885F2RL1 4059/4885CALM1 4770/4885
US-20080269221-A1 ANTIBACTERIAL AGENTS MRPL21, SI, PGLS ALOX5 1393/4885F2RL1 4059/4885CALM1 4770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.