Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22711060 | 0.86 | THRB (0.45) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL115658 | 0.84 | KIF11 (0.46) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL6384941 | 0.82 | KCNN4 (0.38) | POLBTSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL19012586 | 0.82 | THRB (0.44) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL10632044 | 0.80 | CYP2C19 (0.41) | TSHRCHRM2CHRM1CHRM3CYP2D6 | |
| SCHEMBL16026396 | 0.80 | LMNA (0.33) | HTTTSHRCHRM2CHRM1CHRM3 | |
| SCHEMBL871073 | 0.78 | CYP2C19 (0.41) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL1325115 | 0.78 | TSHR (0.45) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL9848763 | 0.78 | CES1 (0.51) | THRBPOLBAPEX1HTTTDP1 | |
| SCHEMBL10895273 | 0.77 | THRB (0.39) | THRBPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454258-A | COPOLYMERS OF UNSATURATED ESTERS AS BINDERS FOR POWDERED FILLERS | KANEBO LTD. (JP) | 1984-06-12 | — | — | US | disclosed |
| US-4440878-A | NITRIDE AND BINDER BASED ON A PENTAERYTHRITOL ACRYLATE MONOMER; CURING; BONDING | KANEBO, LTD. (JP) | 1984-04-03 | — | — | US | disclosed |
| EP-0092260-A1 | A composition of restorative material | KANEBO, LTD. (JP) | 1983-10-26 | — | — | EP | disclosed |
| US-4327014-A | INORGANIC NITRIDE FILLERS IN BINDERS OF PENTAERYTHRITOL TRI-OR TETRA-ACRYLATES | KANEBO LTD. (JP) | 1982-04-27 | — | — | US | disclosed |
| EP-0017936-A2 | Compositions of restorative material especially suitable for dental filling material | KANEBO, LTD. (JP) | 1980-10-29 | — | — | EP | disclosed |