SCHEMBL11054831

SCHEMBL11054831

O=CNNc1ccc(NC(=O)Nc2cccs2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 17/20 0.64
MAPT P10636 17/20 0.64
MEN1 O00255 12/20 0.64
KMT2A Q03164 12/20 0.64
ALOX15 P16050 12/20 0.64
HSD17B10 Q99714 11/20 0.64
RAB9A P51151 9/20 0.64
TP53 P04637 7/20 0.64
SMN1; SMN2 Q16637 7/20 0.64
NPC1 O15118 6/20 0.64
GFER P55789 2/20 0.64
HTT P42858 7/20 0.59
USP2 O75604 2/20 0.59
POLB P06746 2/20 0.59
ALDH1A1 P00352 5/20 0.52
KDM4E B2RXH2 3/20 0.52
MAPK1 P28482 3/20 0.52
LMNA P02545 2/20 0.50
CYP1A2 P05177 1/20 0.49
CYP2C9 P11712 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11049255 0.79 GAA (0.64) GAAMAPTMEN1KMT2AALOX15
SCHEMBL11968855 0.79 GAA (0.73) GAAMAPTMEN1KMT2AALOX15
SCHEMBL10797576 0.79 SMN1; SMN2 (0.63) MAPTMEN1KMT2ARAB9ATP53
SCHEMBL9547640 0.79 GAA (0.72) GAAMAPTMEN1KMT2AALOX15
SCHEMBL11968803 0.78 GAA (0.71) GAAMAPTMEN1KMT2AALOX15
SCHEMBL203356 0.75
SCHEMBL9785803 0.74 MEN1 (0.56) MAPTMEN1KMT2ARAB9ASMN1; SMN2
SCHEMBL11054842 0.74 ALDH1A1 (0.53) GAAMAPTMEN1KMT2AALOX15
SCHEMBL12204416 0.73 MAPT (0.67) GAAMAPTMEN1KMT2AALOX15
SCHEMBL11058560 0.73 ALDH1A1 (0.56) MAPTKMT2ARAB9ATP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4482627-A USING A UREIDO-CONTAINING HYDRAZIDE AS FOGGING AGENT AND A THIOUREA; SHARPNESS FUJI PHOTO FILM CO., LTD. (JP) 1984-11-13 US disclosed
US-4374923-A FOGGING FUJI PHOTO FILM CO., LTD. (JP) 1983-02-22 US disclosed
US-4323643-A HIGH CONTRAST USING UREIDO ARYLHYDRAZIDE COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 1982-04-06 US disclosed