SCHEMBL11054842

SCHEMBL11054842

Cc1ccc(NC(=O)Nc2ccc(NNC=O)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
MAPT P10636 3/20 0.53
PTPN7 P35236 1/20 0.51
RAB9A P51151 11/20 0.50
SMN1; SMN2 Q16637 5/20 0.50
TDP1 Q9NUW8 1/20 0.50
NPC1 O15118 9/20 0.49
MEN1 O00255 2/20 0.49
TP53 P04637 2/20 0.49
KMT2A Q03164 2/20 0.49
GAA P10253 1/20 0.49
ALOX15 P16050 1/20 0.49
GFER P55789 1/20 0.49
HSD17B10 Q99714 1/20 0.49
EPHX1 P07099 1/20 0.49
TGM2 P21980 1/20 0.49
POLB P06746 3/20 0.48
GBA1 P04062 1/20 0.47
LMNA P02545 1/20 0.47
HTT P42858 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6673208 0.87 TDP1 (0.45) ALDH1A1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL27895985 0.85 RAB9A (0.71) ALDH1A1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL11058560 0.84 ALDH1A1 (0.56) ALDH1A1MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL16743890 0.84 TGM2 (0.55) ALDH1A1MAPTPTPN7RAB9ASMN1; SMN2
SCHEMBL10797576 0.84 SMN1; SMN2 (0.63) MAPTRAB9ASMN1; SMN2NPC1MEN1
SCHEMBL1275920 0.82 ALDH1A1 (0.70) ALDH1A1MAPTPTPN7RAB9ASMN1; SMN2
SCHEMBL9785803 0.82 MEN1 (0.56) ALDH1A1MAPTRAB9ASMN1; SMN2NPC1
SCHEMBL10794415 0.81 RAB9A (0.71) MAPTRAB9ASMN1; SMN2NPC1MEN1
SCHEMBL9785812 0.79 SMN1; SMN2 (0.57) ALDH1A1MAPTRAB9ASMN1; SMN2TDP1
SCHEMBL11054531 0.79 MTNR1B (0.46) ALDH1A1MAPTRAB9ANPC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4482627-A USING A UREIDO-CONTAINING HYDRAZIDE AS FOGGING AGENT AND A THIOUREA; SHARPNESS FUJI PHOTO FILM CO., LTD. (JP) 1984-11-13 US disclosed
US-4374923-A FOGGING FUJI PHOTO FILM CO., LTD. (JP) 1983-02-22 US disclosed