SCHEMBL11054849

SCHEMBL11054849

C=C(O)Cc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
SRD5A2 P31213 3/20 0.55
ATM Q13315 2/20 0.50
ACHE P22303 1/20 0.49
L3MBTL1 Q9Y468 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
LMNA P02545 2/20 0.47
RAB9A P51151 2/20 0.47
MAPT P10636 1/20 0.47
MAPK13 O15264 1/20 0.47
MAPK12 P53778 1/20 0.47
MAPK11 Q15759 1/20 0.47
MAPK14 Q16539 1/20 0.47
HTT P42858 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
HPGD P15428 3/20 0.46
ELANE P08246 1/20 0.46
NPC1 O15118 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8664447 0.85 ALDH1A1 (0.52) ALDH1A1SRD5A2ATML3MBTL1TDP1
SCHEMBL1415906 0.83 SRD5A2 (0.73) ALDH1A1SRD5A2ATML3MBTL1TDP1
SCHEMBL29163965 0.82 SRD5A2 (0.79) ALDH1A1SRD5A2ATML3MBTL1TDP1
Methane SCHEMBL11705397 0.82 SRD5A2 (0.71) ALDH1A1SRD5A2ATML3MBTL1TDP1
SCHEMBL7804120 0.80 ALDH1A1 (0.56) ALDH1A1SRD5A2ATML3MBTL1TDP1
SCHEMBL8719473 0.80 ALDH1A1 (0.56) ALDH1A1SRD5A2ATML3MBTL1TDP1
SCHEMBL7936989 0.80 ALDH1A1 (0.56) ALDH1A1SRD5A2ATML3MBTL1TDP1
SCHEMBL16162416 0.80 ALDH1A1 (0.56) ALDH1A1SRD5A2ATML3MBTL1TDP1
SCHEMBL27504159 0.79 CYP4F2 (0.56) ALDH1A1SRD5A2ATMACHEL3MBTL1
SCHEMBL5546768 0.79 ALDH1A1 (0.61) ALDH1A1SRD5A2ATML3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4464496-A BLEND CONTAINING EPM OR EPDM GRAFT POLYMER, ANTIOXIDANT-UV STABILIZER COMBINATION UNIROYAL, INC. (US) 1984-08-07 US disclosed
EP-0090530-A2 Non-yellowing polymer composition THE DOW CHEMICAL COMPANY (US) 1983-10-05 EP disclosed