Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | GFER | P55789 | 3/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.57 |
| ▸ | GLA | P06280 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | PKM | P14618 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6322764 | 0.86 | ALDH1A1 (0.76) | ALDH1A1NPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL13599850 | 0.79 | NPC1 (0.81) | ALDH1A1NPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL13183701 | 0.77 | NPC1 (0.78) | ALDH1A1NPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL15496393 | 0.75 | NPC1 (0.66) | ALDH1A1NPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL2245390 | 0.75 | ALDH1A1 (0.61) | ALDH1A1NPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL363703 | 0.74 | MEN1 (1.00) | ALDH1A1NPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL15443953 | 0.74 | MEN1 (0.87) | ALDH1A1NPC1MAPTSMN1; SMN2MEN1 | |
| Barbituric Acid SCHEMBL28365746 | 0.74 | ACHE (0.52) | ALDH1A1NPC1MAPTMEN1KMT2A | |
| SCHEMBL21096315 | 0.74 | NT5E (0.86) | ALDH1A1NPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL6124301 | 0.73 | NPC1 (0.71) | ALDH1A1NPC1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451398-A | Dyes containing imidazolymethylene groups | BASF AKTIENGESELLSCHAFT (DE) | 1984-05-29 | — | — | US | disclosed |